Marengo's bispecific antibody, Invikafusp alfa, demonstrated an objective response in eight tumor types during Phase 2 trials, particularly benefiting patients unresponsive to prior checkpoint inhibitors. This first-in-class dual T cell agonist shows promise in expanding treatment options for difficult-to-treat cancers.
Invikafusp alfa, a first-in-class dual T cell agonist, showed an objective response in various types of cancer, particularly among patients who did not respond to previous checkpoint inhibitor therapy.
Original title: “ESMO 2026: Marengo's bispecific antibody shrinks 8 tumor types in Phase 2”