prevalence of major pulmonary complications among patients with systemic lupus erythematosus sle a systematic review and meta analysis

Original title: “Prevalence of Major Pulmonary Complications Among Patients with Systemic Lupus Erythematosus (SLE): A Systematic Review and Meta-Analysis.”

lupus associated hypophysitis a narrative systematic review of clinical radiological and endocrine features

Original title: “Lupus‑Associated Hypophysitis: A Narrative Systematic Review of Clinical, Radiological and Endocrine Features.”

optimizing hydroxychloroquine blood levels and long term hydroxychloroquine intake could lower ascvd risk and prevent polypharmacy in systemic lupus erythematosus

Original title: “Optimizing Hydroxychloroquine Blood Levels and Long-Term Hydroxychloroquine Intake Could Lower ASCVD Risk and Prevent Polypharmacy in Systemic Lupus Erythematosus.”

inaugural complete heart block in anti ssa negative systemic lupus erythematosus the diagnostic role of anti pm scl 100 antibodies

Original title: “Inaugural complete heart block in anti-SSA negative systemic lupus erythematosus: the diagnostic role of anti-PM-Scl 100 antibodies.”

targeting type i interferon in lupus autoimmune haemolytic anaemia first report with anifrolumab

Original title: “Targeting type I interferon in lupus autoimmune haemolytic anaemia: first report with anifrolumab.”

autoimmune myelofibrosis secondary to systemic lupus erythematosus a diagnostic challenge in a resource limited setting

Original title: “Autoimmune myelofibrosis secondary to systemic lupus erythematosus: a diagnostic challenge in a resource-limited setting.”

challenge of innovation in lupus between abstraction and reality

Original title: “The challenge of innovation in lupus between abstraction and reality.”

progressive podocyte infolding glomerulopathy in a patient with systemic lupus erythematosus revealed by serial renal biopsies a case report and literature review

Original title: “Progressive podocyte infolding glomerulopathy in a patient with systemic lupus erythematosus revealed by serial renal biopsies: a case report and literature review.”

when lupus strikes twice pancreatitis and nephritis in an overlap syndrome a rare multisystem flare

Original title: “When Lupus Strikes Twice: Pancreatitis and Nephritis in an Overlap Syndrome - A Rare Multisystem Flare.”

bcma cd19 car t cells in systemic lupus erythematosus humoral reset or antigen specific tolerance

Original title: “BCMA-CD19 CAR T Cells in Systemic Lupus Erythematosus: Humoral Reset or Antigen-Specific Tolerance?”

pregnancy and lactation during anifrolumab treatment in systemic lupus erythematosus

Original title: “Pregnancy and lactation during anifrolumab treatment in systemic lupus erythematosus.”

clinical features and outcomes of patients with anti neutrophil cytoplasmic antibody positive systemic lupus erythematosus from a single center retrospective study

Original title: “Clinical features and outcomes of patients with anti-neutrophil cytoplasmic antibody-positive systemic lupus erythematosus from a single-center retrospective study.”

progression of skin limited pediatric onset discoid lupus erythematosus to diagnosis of systemic lupus erythematosus results of a multicenter retrospective cohort study

Original title: “Progression of skin-limited pediatric-onset discoid lupus erythematosus to diagnosis of systemic lupus erythematosus: results of a multicenter, retrospective cohort study.”

bone marrow infiltration of large b cell lymphoma with clinical manifestations similar to systemic lupus erythematosus a case report

Original title: “[Bone marrow infiltration of large B-cell lymphoma with clinical manifestations similar to systemic lupus erythematosus: A case report].”

The therapy works by genetically modifying cells to enable the body’s own immune system to recognise and attack problem cells I’m taking every gift that UCLH and that trial has given me, and I’m running with it.” · The new study enrolled nine patients aged 12 to 65 with active, severe disease who had not responded to multiple treatments for lupus. ... Senior Clinical Practice Facilitator Nicole Prescott administering breakthrough treatment to patient Katie Tinkler for lupus at University College London Hospital in London (PA) “These findings provide early evidence that CAR T-cell therapy may be able to reset the immune system and drive meaningful clinical improvements after a single treatment. “Although these are still early days, the results mark an important step forward in exploring how cellular therapies could transform the treatment of autoimmune diseases.” ... In the new NHS trial, led by University College London Hospitals NHS Foundation Trust (UCLH) and University College London (UCL), five out of six patients with severe lupus went into remission within a few months of receiving CAR-T (PA) A new NHS trial, spearheaded by University College London Hospitals NHS Foundation Trust (UCLH) and University College London (UCL), saw five out of six severe lupus patients achieve remission within months of CAR-T treatment. Over an average 11-month follow-up, rapid improvements in disease markers were observed, including stabilisation or enhancement of kidney function previously damaged by lupus. The CAR-T in the trial was obecabtagene autoleucel (obe-cel), developed by UCL spinout firm Autolus Therapeutics. Obe-cel is designed to target and deplete CD19-positive B cells, which play a central role in lupus. Katie Tinkler was forced to give up her job as a fitness instructor because of debilitating pain and fatigue caused by the severe lupus she has had since she was 20. Lupus caused her to suffer very swollen and painful joints, kidney damage that meant she was close to needing dialysis, lung and heart disease, and a tendency to develop blood clots.

Original title: “Groundbreaking NHS immune therapy sees lupus patients go into remission”

hypocomplementemic urticarial vasculitis a rare presentation revealing systemic lupus erythematosus and sj gren s disease

Original title: “Hypocomplementemic urticarial vasculitis: a rare presentation revealing systemic lupus erythematosus and Sjögren's disease.”

single cell sequencing in systemic lupus erythematosus

Original title: “Single-cell sequencing in systemic lupus erythematosus.”

clinicopathological characteristics and renal outcomes of iga nephropathy in systemic lupus erythematosus a case report and systematic literature review

Original title: “Clinicopathological characteristics and renal outcomes of IgA nephropathy in systemic lupus erythematosus: a case report and systematic literature review.”

dna engineered dual signal biomimetic fusion vesicles for rapid evaluation of systemic lupus erythematosus

Original title: “DNA-Engineered Dual-Signal Biomimetic Fusion Vesicles for Rapid Evaluation of Systemic Lupus Erythematosus.”

diffuse splenic calcifications in systemic lupus erythematosus a case based review

Original title: “Diffuse splenic calcifications in systemic lupus erythematosus: a case-based review.”