Explore Diseases Find Orgs Patient Assistance News Insights About

Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

Open rare disease resources — free, sourced, never gated.

Resources

Rare Disease Directory
Patient Organization Directory
Patient Assistance Programs
Rare Disease News
Clinical Trials
Research Publications

Legal

Privacy Policy
Terms of Service
Accessibility
About & Methodology
Contact

polyarticular juvenile rheumatoid arthritis News | Kisho

Not rare diseases news,
news about your rare disease.

Every story we pull is tagged to the disease it’s about — so you can filter to your condition and read only what matters.

News sourcesFDA·NIH·CDC·EMA·PubMed·Federal Register·NORD·EURORDIS·Global Genes·The Mighty·BioPharma Dive·BioSpace

Newsroom26 Trends

Daily Briefings

Showing news related to

polyarticular juvenile rheumatoid arthritis

26 articles

View Disease

polyarticular juvenile rheumatoid arthritis

Earlier

20 stories

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

Researchers developed a new humanized TCR transgenic mouse model to study T cells that react to citrullinated tenascin C, an important autoantigen in rheumatoid arthritis. This model could enhance understanding of the disease mechanisms and potential therapeutic targets.

new humanised tcr transgenic mouse model to study t cells reactive to citrullinated tenascin c a relevant autoantigen in rheumatoid arthritis

PubMed Rare Disease·10 days ago·Read at source →

Original title: “A new humanised TCR transgenic mouse model to study T cells reactive to citrullinated tenascin C, a relevant autoantigen in rheumatoid arthritis.”

COVID-19 rheumatoid arthritis+1 moreResearch

A case study highlights the occurrence of a giant abdominal hematoma and rapid multidrug-resistant infection in a patient with COVID-19 and rheumatoid arthritis following low-molecular-weight heparin treatment. This finding underscores potential complications in managing anticoagulation in patients with complex comorbidities.

giant abdominal haematoma and rapid multidrug resistant infection after low molecular weight heparin in a patient with covid 19 and rheumatoid arthritis

PubMed Rare Disease·15 days ago·Read at source →

Original title: “Giant Abdominal Haematoma and Rapid Multidrug-Resistant Infection After Low-Molecular-Weight Heparin in a Patient With COVID-19 and Rheumatoid Arthritis.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A multicenter observational study by GIRRCS evaluates the effectiveness and safety of Janus Kinase inhibitors in patients with rheumatoid arthritis. The findings contribute to the understanding of real-life outcomes for this treatment class.

effectiveness and safety of janus kinase inhibitors in patients with rheumatoid arthritis results from a multicenter observational real life girrcs gruppo italiano di ricerca in reumatologia clinica e sperimentale study

PubMed Rare Disease·18 days ago·Read at source →

Original title: “Effectiveness and safety of Janus Kinase inhibitors in patients with rheumatoid arthritis, results from a multicenter observational "real-life" GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A recent study compares denosumab and alendronate in reducing fracture risk and improving bone metabolism among postmenopausal rheumatoid arthritis patients on glucocorticoids. The findings contribute to understanding treatment options for this patient population.

comparison of the effects of denosumab and alendronate on fracture risk and bone metabolism in postmenopausal rheumatoid arthritis patients treated with oral glucocorticoids a propensity score matched retrospective cohort study

PubMed Rare Disease·about 1 month ago·Read at source →

Original title: “Comparison of the effects of denosumab and alendronate on fracture risk and bone metabolism in postmenopausal rheumatoid arthritis patients treated with oral glucocorticoids: A propensity score-matched retrospective cohort study.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A recent case study highlights a rare presentation of rheumatoid arthritis leading to airway obstruction due to cricoarytenoid arthritis. This finding underscores the need for awareness of atypical manifestations of common diseases.

case of rheumatoid arthritis presenting with airway obstruction from cricoarytenoid arthritis

PubMed Rare Disease·about 1 month ago·Read at source →

Original title: “A Case of Rheumatoid Arthritis Presenting With Airway Obstruction From Cricoarytenoid Arthritis.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A new study analyzes vaccine adverse events related to rheumatoid arthritis using the VAERS database. This pharmacovigilance research provides insights into the safety profile of vaccines in patients with this autoimmune condition.

analysis of vaccine adverse events associated with rheumatoid arthritis a pharmacovigilance study based on the vaers database

PubMed Rare Disease·about 2 months ago·Read at source →

Original title: “Analysis of vaccine adverse events associated with rheumatoid arthritis: A pharmacovigilance study based on the VAERS database.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A systematic review highlights the connection between rheumatoid arthritis and multisite cardiac aneurysms, specifically involving the left ventricular outflow tract and valves. This case-based analysis provides insights into the cardiovascular complications associated with rheumatoid arthritis.

rheumatoid arthritis and multisite cardiac aneurysms involving the lvot valves and intervalvular fibrosa a case based systematic review

PubMed Rare Disease·about 2 months ago·Read at source →

Original title: “Rheumatoid arthritis and multisite cardiac aneurysms involving the LVOT, valves, and intervalvular Fibrosa: A case-based systematic review.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A case report details a rare instance of pubic symphysis osteomyelitis in a patient with rheumatoid arthritis, highlighting the need for awareness of atypical presentations in such patients. This case emphasizes the importance of differential diagnosis in managing groin pain.

pubic symphysis osteomyelitis presenting as groin pain in a patient with rheumatoid arthritis a case report

PubMed Rare Disease·2 months ago·Read at source →

Original title: “Pubic symphysis osteomyelitis presenting as groin pain in a patient with rheumatoid arthritis: a case report.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritis+1 moreResearch

A case series of six patients reveals clinical features and HLA phenotypes associated with both rheumatoid arthritis and granulomatosis with polyangiitis, highlighting predominant myeloperoxidase (MPO)-ANCA positivity. The study emphasizes the HLA-DR4/DQ8/DPB1*04:01 phenotype in these patients.

clinical features anti neutrophil cytoplasmic antibody anca status and human leucocyte antigen hla phenotypes of patients diagnosed with both rheumatoid arthritis and granulomatosis with polyangiitis a case series of six patients with predominant myeloperoxidase mpo anca positivity and hla dr4 dq8 dpb1 04 01 phenotype

PubMed Rare Disease·3 months ago·Read at source →

Original title: “Clinical features, anti-neutrophil cytoplasmic antibody (ANCA) status, and human leucocyte antigen (HLA) phenotypes of patients diagnosed with both rheumatoid arthritis and granulomatosis with polyangiitis: a case series of six patients with predominant myeloperoxidase (MPO)-ANCA positivity and HLA-DR4/DQ8/DPB1*04:01 phenotype.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisTrials & approvals

Rise Therapeutics has completed enrollment in the 4-week dose expansion cohort of its Phase 1b clinical trial for R-2487 in patients with active rheumatoid arthritis. This advancement allows for further evaluation of the therapy, with data expected to be presented at upcoming rheumatology and immunology conferences.

/PRNewswire/ -- Rise Therapeutics, a clinical-stage biotechnology company advancing novel oral immunotherapies for autoimmune diseases, today announced the... ROCKVILLE, MD, June 2, 2026 /PRNewswire/ -- Rise Therapeutics, a clinical-stage biotechnology company advancing novel oral immunotherapies for autoimmune diseases, today announced the completion of full enrollment in the 4-week dose expansion cohort of its Phase 1b clinical trial (NCT05961592) evaluating orally dosed R-2487 in patients with active rheumatoid arthritis (RA). This recommendation marks an important advancement for the R-2487 clinical program and enables continued evaluation of the therapy over an extended treatment period. Data from the 4-week dose expansion cohort will be presented at upcoming national and international rheumatology and immunology conferences, as appropriate and as analyses become available. Dr. Fanger added: "In parallel with the ongoing clinical expansion cohorts evaluating extended dosing and enrolling patients with overlapping RA and Sjögren's disease, we are preparing R-2487 for the next stage of clinical development. This includes advancing clinical protocol design, dose selection strategy, and regulatory engagement to support a Phase 2 clinical evaluation. We are also scaling key operational capabilities, including GMP manufacturing, to enable an efficient transition into the next phase of development for this program." RA is a multi-billion-dollar global market with continued demand for therapies that combine early intervention, improved tolerability, and disease-modifying potential. With internal GMP manufacturing capabilities and a growing clinical pipeline, Rise Therapeutics is positioned to advance multiple programs targeting autoimmune and inflammatory diseases while pursuing value-creating partnerships and strategic growth opportunities, including the continued advancement of R-2487 into Phase 2 clinical development.

Treatment & Clinical News·4 months ago·Read at source →

Original title: “Rise Therapeutics Completes Enrollment in Four-Week Dose Expansion Cohort for the R-2487 Rheumatoid Arthritis Clinical Trial”

pyoderma gangrenosum pyoderma gangrenosum-acne-suppurative hidradenitis syndrome+1 moreResearch

A recent study highlights pyoderma gangrenosum as a manifestation of multisystem autoimmunity in a patient with giant cell arteritis, optic neuritis, and rheumatoid arthritis. This research contributes to understanding the complex interplay of autoimmune diseases.

pyoderma gangrenosum as a manifestation of multisystem autoimmunity in a patient with giant cell arteritis optic neuritis and rheumatoid arthritis

PubMed Rare Disease·4 months ago·Read at source →

Original title: “Pyoderma gangrenosum as a manifestation of multisystem autoimmunity in a patient with giant cell arteritis, optic neuritis and rheumatoid arthritis.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A new study discusses the importance of clinical judgment in the use of JAK inhibitors for rheumatoid arthritis, challenging the current categorical exclusion practices. This research highlights the need for a more nuanced approach to treatment decisions.

beyond categorical exclusion reclaiming clinical judgment in the use of jak inhibitors for rheumatoid arthritis

PubMed Rare Disease·4 months ago·Read at source →

Original title: “Beyond categorical exclusion: Reclaiming clinical judgment in the use of JAK inhibitors for rheumatoid arthritis.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A case study highlights bilateral insufficient calcaneus fractures in a patient with rheumatoid arthritis, presenting a unique clinical observation. This finding may inform future research on fracture risks in patients with rheumatoid arthritis.

case of bilateral but not unilateral insufficient calcaneus fractures in a patient with rheumatoid arthritis suffering from talalgia

PubMed Rare Disease·4 months ago·Read at source →

Original title: “A case of bilateral but not unilateral insufficient calcaneus fractures in a patient with rheumatoid arthritis suffering from talalgia.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A case report highlights the diagnostic and therapeutic challenges faced in an 18-year-old Saudi female with seropositive rheumatoid arthritis and MRI-confirmed sacroiliitis. This case underscores the complexities of managing coexisting conditions in young patients.

seropositive rheumatoid arthritis with concomitant mri confirmed sacroiliitis in an 18 year old saudi female a case report of diagnostic and therapeutic challenges

PubMed Rare Disease·4 months ago·Read at source →

Original title: “Seropositive rheumatoid arthritis with concomitant MRI confirmed sacroiliitis in an 18-year-old Saudi female: A case report of diagnostic and therapeutic challenges.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A recent study investigates the oral colonization of Pneumocystis jirovecii in patients with rheumatoid arthritis experiencing respiratory symptoms. This research adds to the understanding of potential respiratory complications in this patient population.

oral colonization of pneumocystis jirovecii in patients with rheumatoid arthritis and respiratory symptoms a substudy of the aurora cohort

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Oral colonization of Pneumocystis jirovecii in patients with rheumatoid arthritis and respiratory symptoms: a substudy of the AURORA cohort.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A recent study investigates how disease duration affects forefoot involvement in patients with rheumatoid arthritis in remission. The research utilizes clinical, ultrasound, and radiographic assessments to provide insights into the condition's progression.

impact of disease duration on forefoot involvement in rheumatoid arthritis remission clinical ultrasound and radiographic insights

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Impact of disease duration on forefoot involvement in rheumatoid arthritis remission: clinical, ultrasound, and radiographic insights.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A recent study analyzes the vaginal microenvironment in patients with rheumatoid arthritis, providing insights into potential interactions between autoimmune conditions and vaginal health. This research could inform future therapeutic strategies for managing symptoms in affected individuals.

cross sectional analysis of the vaginal microenvironment in rheumatoid arthritis

PubMed Rare Disease·5 months ago·Read at source →

Original title: “A cross-sectional analysis of the vaginal microenvironment in rheumatoid arthritis.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A recent study analyzes the impact of postpartum changes on patients with rheumatoid arthritis and spondyloarthritis, providing insights into disease management during this critical period. The findings contribute to understanding the complexities of these conditions in the context of postpartum health.

impact of postpartum on patients with rheumatoid arthritis and spondyloarthritis an ancillary analysis of the gr2 prospective cohort

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Impact of postpartum on patients with rheumatoid arthritis and spondyloarthritis: an ancillary analysis of the GR2 prospective cohort.”

osteonecrosis of the jaw rheumatoid arthritis+1 moreResearch

A recent clinical analysis highlights the risk factors for osteonecrosis of the jaw in patients with rheumatoid arthritis, emphasizing the need for improved oral health management in this population. The findings could inform future research and clinical practices.

clinical analysis of osteonecrosis of the jaw in patients with rheumatoid arthritis risk factors and oral health implications

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Clinical analysis of osteonecrosis of the jaw in patients with rheumatoid arthritis: risk factors and oral health implications.”

rheumatoid arthritis polyarticular juvenile rheumatoid arthritisResearch

A real-world observational study in Italy shows that upadacitinib effectively achieves and maintains remission in patients with moderate-to-severe rheumatoid arthritis over one year. This data supports the drug's role in long-term management of the disease.

achievement and maintenance of remission with upadacitinib in patients with moderate to severe rheumatoid arthritis in italy 1 year data from uphold a prospective real world observational study

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Achievement and Maintenance of Remission with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in Italy: 1-Year Data from UPHOLD, a Prospective Real-World Observational Study.”

1 / 2Next

Daily Briefings

Not rare diseases news,news about your rare disease.

Earlier

Researchers developed a new humanized TCR transgenic mouse model to study T cells that react to citrullinated tenascin C, an important autoantigen in rheumatoid arthritis. This model could enhance understanding of the disease mechanisms and potential therapeutic targets.

A multicenter observational study by GIRRCS evaluates the effectiveness and safety of Janus Kinase inhibitors in patients with rheumatoid arthritis. The findings contribute to the understanding of real-life outcomes for this treatment class.

A recent study compares denosumab and alendronate in reducing fracture risk and improving bone metabolism among postmenopausal rheumatoid arthritis patients on glucocorticoids. The findings contribute to understanding treatment options for this patient population.

A recent case study highlights a rare presentation of rheumatoid arthritis leading to airway obstruction due to cricoarytenoid arthritis. This finding underscores the need for awareness of atypical manifestations of common diseases.

A new study analyzes vaccine adverse events related to rheumatoid arthritis using the VAERS database. This pharmacovigilance research provides insights into the safety profile of vaccines in patients with this autoimmune condition.

A systematic review highlights the connection between rheumatoid arthritis and multisite cardiac aneurysms, specifically involving the left ventricular outflow tract and valves. This case-based analysis provides insights into the cardiovascular complications associated with rheumatoid arthritis.

A case report details a rare instance of pubic symphysis osteomyelitis in a patient with rheumatoid arthritis, highlighting the need for awareness of atypical presentations in such patients. This case emphasizes the importance of differential diagnosis in managing groin pain.

A case series of six patients reveals clinical features and HLA phenotypes associated with both rheumatoid arthritis and granulomatosis with polyangiitis, highlighting predominant myeloperoxidase (MPO)-ANCA positivity. The study emphasizes the HLA-DR4/DQ8/DPB1*04:01 phenotype in these patients.

A recent study highlights pyoderma gangrenosum as a manifestation of multisystem autoimmunity in a patient with giant cell arteritis, optic neuritis, and rheumatoid arthritis. This research contributes to understanding the complex interplay of autoimmune diseases.

A new study discusses the importance of clinical judgment in the use of JAK inhibitors for rheumatoid arthritis, challenging the current categorical exclusion practices. This research highlights the need for a more nuanced approach to treatment decisions.

A case study highlights bilateral insufficient calcaneus fractures in a patient with rheumatoid arthritis, presenting a unique clinical observation. This finding may inform future research on fracture risks in patients with rheumatoid arthritis.

A case report highlights the diagnostic and therapeutic challenges faced in an 18-year-old Saudi female with seropositive rheumatoid arthritis and MRI-confirmed sacroiliitis. This case underscores the complexities of managing coexisting conditions in young patients.

A recent study investigates the oral colonization of Pneumocystis jirovecii in patients with rheumatoid arthritis experiencing respiratory symptoms. This research adds to the understanding of potential respiratory complications in this patient population.

A recent study investigates how disease duration affects forefoot involvement in patients with rheumatoid arthritis in remission. The research utilizes clinical, ultrasound, and radiographic assessments to provide insights into the condition's progression.

A recent study analyzes the vaginal microenvironment in patients with rheumatoid arthritis, providing insights into potential interactions between autoimmune conditions and vaginal health. This research could inform future therapeutic strategies for managing symptoms in affected individuals.

A recent clinical analysis highlights the risk factors for osteonecrosis of the jaw in patients with rheumatoid arthritis, emphasizing the need for improved oral health management in this population. The findings could inform future research and clinical practices.

A real-world observational study in Italy shows that upadacitinib effectively achieves and maintains remission in patients with moderate-to-severe rheumatoid arthritis over one year. This data supports the drug's role in long-term management of the disease.

Not rare diseases news,
news about your rare disease.