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NIH Grants & Funding for 22q11.2 Deletion Syndrome | Kisho | Kisho

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22q11.2 Deletion Syndrome — NIH Grants & Funding

Active and recent NIH-funded research on 22q11.2 Deletion Syndrome. Data from NIH RePORTER, last 36 months.

MONDO:0018923

Looking for specific grants? The Recent Research tab lets you search and filter by topic.

Funding Landscape

22q11.2 Deletion Syndrome has a robust NIH research funding landscape with 28 funded grants and $29.8M in total funding over the period.

28funded grants from NIH

Portfolio: $11.2MCumulative: $29.8M16 active12 completed29 PIs15 institutions

-6% YoY(FY2024 vs FY2025)

1 new grant started in the last 12 months.

By Research Theme

Basic Science

Translational

Clinical

Epi / Nat. History

1 additional grant classified as “Other” (multi-disciplinary, infrastructure, etc.).

Funding by Fiscal Year

NIH fiscal year (Oct–Sep)

$7.7M

FY22

$7.3M

FY23

$7.1M

FY24

$6.7M

FY25

$1.0M

FY26

By Funding Mechanism

R01

R21

F30

F31

K00

K08

Funding Gap Analysis

Cross-referencing NIH grants against published research and clinical trials to identify funding-evidence gaps for 22q11.2 Deletion Syndrome. Strongest funded area: Basic Science. Largest gap: Biomarker / Diagnostics.

Biomarker / DiagnosticsPublished, Not NIH-Funded

19 publications in Diagnostic / Biomarker but no NIH-funded grants found in Biomarker / Diagnostics for 22q11.2 deletion syndrome. Existing research activity suggests this may be a viable area for grant applications.

Adjacent Research(12 grants)

These grants mention 22q11.2 Deletion Syndrome as part of broader research but are not primarily focused on this disease. They are not included in the funding totals above.

Other(12)

OtherZIACompleted

Neural Crest Development and Disease

Kerosuo, Laura·NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH

$1,837,179 (FY2025)

NIH RePORTER

OtherP50Active

MIND Institute Intellectual and Developmental Disabilities Research Center

ABBEDUTO, LEONARD et al.·UNIVERSITY OF CALIFORNIA AT DAVIS·DAVIS, CA

$1,252,036 (FY2024)

NIH RePORTER

OtherR44Active

Development of a stem-cell derived thymic cell therapy to treat patients with athymia

LIM, BING·THYMMUNE THERAPEUTICS, INC·CAMBRIDGE, MA

$1,000,000 (FY2025)

NIH RePORTER

OtherP50Active

SUPPORT FOR THE ROSE F KENNEDY IDDRC P50

MOLHOLM, SOPHIE et al.·ALBERT EINSTEIN COLLEGE OF MEDICINE·BRONX, NY

$1,000,000 (FY2025)

NIH RePORTER

OtherR01Active

1/2: Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood

Gur, Raquel·UNIVERSITY OF PENNSYLVANIA·PHILADELPHIA, PA

$869,897 (FY2026)

NIH RePORTER

OtherR01Active

Understanding kidney failure in individuals with DiGeorge syndrome

SAMPOGNA, ROSEMARY et al.·COLUMBIA UNIVERSITY HEALTH SCIENCES·NEW YORK, NY

$859,998 (FY2026)

NIH RePORTER

OtherR01Completed

Molecular and cellular mechanisms in cardiac outflow tract formation and defects

MORROW, BERNICE et al.·UNIVERSITY OF CHICAGO·CHICAGO, IL

$527,857 (FY2024)

NIH RePORTER

OtherR01Active

2/2 - Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood

McDonald-McGinn, Donna·CHILDREN'S HOSP OF PHILADELPHIA·PHILADELPHIA, PA

$484,313 (FY2026)

NIH RePORTER

OtherR01Active

Identification of compensatory mechanisms to rescue aortic arch artery defects

Astrof, Sophie·RUTGERS BIOMEDICAL AND HEALTH SCIENCES·Newark, NJ

$468,337 (FY2025)

NIH RePORTER

OtherU01Completed

Leveraging rare genetic etiologies to advance knowledge and treatment of neuropsychiatric disorders

Ledbetter, David et al.·GEISINGER CLINIC·DANVILLE, PA

$1,826,721 (FY2023)

NIH RePORTER

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22q11.2 Deletion Syndrome — NIH Grants & Funding

Funding Landscape

By Research Theme

Funding by Fiscal Year

By Funding Mechanism

Funding Gap Analysis

Adjacent Research(12 grants)

Other(12)

Neural Crest Development and Disease

MIND Institute Intellectual and Developmental Disabilities Research Center

Development of a stem-cell derived thymic cell therapy to treat patients with athymia

SUPPORT FOR THE ROSE F KENNEDY IDDRC P50

1/2: Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood

Understanding kidney failure in individuals with DiGeorge syndrome

Molecular and cellular mechanisms in cardiac outflow tract formation and defects

2/2 - Neurodevelopmental Trajectories in 22q11.2 Deletion Syndrome in Adolescence and Young Adulthood

Identification of compensatory mechanisms to rescue aortic arch artery defects

Leveraging rare genetic etiologies to advance knowledge and treatment of neuropsychiatric disorders

Top Funded Institutions

Top Principal Investigators