Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

Back to Acute Leukemia

Acute Leukemia — NIH Grants & Funding

Active and recent NIH-funded research on Acute Leukemia. Data from NIH RePORTER, last 36 months.

MONDO:0010643

NIH-funded research on Acute Leukemia

active grants

institutions

226

researchers

new in last 12 mo.

$229.1M in NIH funding over the last 36 months. Data from NIH RePORTER.

I'm looking for:

Or filter by research focus

Only show active grants

Basic Science(92)

Basic ScienceZIACompleted

Detection, prevention and treatment of acute myeloid leukemia (AML) relapse.

Hourigan, Christopher·NATIONAL HEART, LUNG, AND BLOOD INSTITUTE

$2,779,530 (FY2023)

Acute Leukemia — NIH Grants & Funding

Basic Science(92)

Detection, prevention and treatment of acute myeloid leukemia (AML) relapse.

Ceramide-Directed Therapeutics for Treatment of AML

Mechanism and therapeutic implication of RNA-modification-mediated codon-biased translation in acute myeloid leukemia

A Molecular Approach to Dissecting MEK-Mediated Phosphorylation in Pediatric Leukemia

Overcoming resistance to menin patient mutations in leukemia

Targeting PRC1 in leukemia

Dynamic 3D chromatin remodeling in acute leukemia - Resubmission - 1

New control of oncogene activation in T-cell leukemia

Promoting immunity against acute myeloid leukemia through Fc effector-optimized antibody inhibitory of MICA/B shedding

Exploring microRNA degradation in T-cell acute lymphoblastic leukemia

Translational(62)

Specialized Program of Research Excellence (SPORE) in Leukemia

Proteogenomic characterization of early and late resistance mechanisms in acute myeloid leukemia

Development of a Novel Immunotherapeutic for Acute Myeloid Leukemia

Multiplex Epitope Editing to Enable Novel Immunotherapies for Acute Myeloid Leukemia

Development of Novel Immunotherapeutic Strategies for Myeloid Malignancies

Targeting AMP Synthesis to Overcome Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Elucidating the SCP4 pathway as a multi-catalytic signaling dependency in acute myeloid leukemia

Selective targeting of TAF1 function in acute myeloid leukemia

Discovery of First-in-class WDR5 PROTACs as a Novel Therapeutic Strategy for MLL-rearranged Leukemias

Dissecting and targeting canonical and non-canonical oncogenic functions of EZH2 in caner

Clinical(18)

Adult Leukemia Research Center

Selective treatment of acute myeloid leukemia with radioimmunotherapies targeting the active conformation of integrin beta-2

Investigating the Role of VISTA in Driving Immune Evasion in Acute Myeloid Leukemia

The role of inflammation in the regulation of immune response in acute myeloid leukemia

Predicting Relapse at the Time of Diagnosis in Acute Lymphoblastic Leukemia

Pathways of Immune Evasion in Acute Myeloid Leukemia

Treatment-Related Cardiotoxicity in Children with Relapsed Acute Myeloid Leukemia - Natural History, Occurrence and Implications

Developing a Values Elicitation Tool to Improve Treatment Decision-Making in Acute Myeloid Leukemia

The Impact of Frailty on Disease Relapse and Therapy Intensity in Older Adults with Acute Myeloid Leukemia: Biomarkers and Treatment Selection

Pediatric acute lymphoblastic leukemia: Improving outcomes through incorporation of novel targeted therapies into treatment for relapsed and newly diagnosed disease

Epi / Nat. History(9)

Reducing Disparities in Acute Leukemia (REDIAL) Consortium

Towards an inclusive genomic risk classification for acute myeloid leukemia (AML)

A Systems Epidemiology Approach for Predicting Methotrexate Neurotoxicity in Pediatric Acute Leukemia

Aging trajectories and outcomes of older adults with acute myeloid leukemia

Targeting obesity to improve survival from childhood acute lymphoblastic leukemia

Molecular epidemiology of acute lymphoblastic leukemia in children with Down syndrome

Developing Acute Myeloid Leukemia Models with Diverse Ancestral Origins

Integrative Molecular Epidemiology of Neurocognitive Outcomes in Acute Lymphoblastic Leukemia

Racial/ethnic disparities in acute myeloid leukemia survival in the novel therapy era: an exploration of the underlying mechanisms and potential targets for intervention

Gene/Cell Therapy(10)

ROLE OF RNA SEQUESTRATION IN ACUTE MYELOID LEUKEMIA

Myeloid cell-selective, oligonucleotide-based STAT3 inhibition combined with total marrow and lymphoid irradiation for immunotherapy of acute myeloid leukemia

Adoptive T-cell Therapies Targeting Mutations in Hematologic Malignancies

Engineering Natural Killer Cells to Target Acute Myeloid Leukemia with HLA-DR Loss

Structure-guided protein evolution to develop improved natural ligand-based chimeric antigen receptor T cell therapy against CD70 in acute myeloid leukemia

Engineering best in class Acute Myeloid Leukemia (AML) CAR-T therapies by enhancing persistence and defining the immune landscape of AML

Clonal Therapy for Pediatric T-cell Acute Lymphoblastic Leukemia

Targeting FLT3 for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

CONCEPT SBIR - T-CELL RECEPTORS FOR TREATING PEDIATRIC ACUTE MYELOID LEUKEMIA

Multi-functional cellular therapies to overcome tumor heterogeneity and limit toxicity in acute myeloid leukemia

Biomarker / Dx(11)

Development of a Universal Assay for Minimal Residual Disease in Acute Myeloid Leukemia using Duplex Sequencing

Development of a Phenotype-based Predictive Analytic for Acute Myeloid Leukemia

Targeting Protein Arginine Methyltransferases to Eradicate Acute Myeloid Leukemia

UBTF Tandem Duplications in Pediatric Acute Myeloid Leukemia

Investigating novel synthetic lethal epigenetic interactions in Acute Myeloid Leukemia

Analysis of E-selectin Ligands of Human Acute Leukemia Cells and their Biology in Leukemogenesis

Biomarkers of dasatinib response and resistance in T-cell acute lymphoblastic leukemia

Characterizing noncoding GWAS variants in acute lymphoblastic leukemia treatment outcome

Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia

Rapid Acute Leukemia Genomic Profiling with CRISPR enrichment and Real-time long-read sequencing

Medical Device(1)

Ultrasound-based Diagnosis and Monitoring of Neutropenic Enterocolitis in Children with Acute Lymphoblastic Leukemia

Other(5)

Targeting Menin Protein Stability In AML

CCSG - Administrative Supplement - ECIA

Enhancing Venetoclax Activity in Chemoresistant Acute Myeloid Leukemia

Targeting Menin Protein Stability In AML

Investigating the Microenvironmental Dysregulation and Polypharmacy Impact during Acute Myeloid Leukemia in an in vitro model of the human bone marrow and in vivo models.