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Acute myeloid leukemia and myelodysplastic syndromes related to radiation represent a subgroup of therapy-related myeloid neoplasms (t-MN), associated with treatment of an unrelated neoplastic disease with radiation. The neoplastic cells typically harbor unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. Patients frequently present with multilineage dysplasia and cytopenias 5-10 years after exposure.
Biomarker and diagnostic research for acute myeloid leukemia and myelodysplastic syndromes related to radiation has been reported in the published literature.
No clinical trials have been registered for acute myeloid leukemia and myelodysplastic syndromes related to radiation.
12 publications have been identified in PubMed for acute myeloid leukemia and myelodysplastic syndromes related to radiation. Research spans Review / Meta-Analysis (25%), Basic Science / Preclinical (25%), and Clinical Trial Publication (17%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 3 | 25% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 7:13 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Laboratory research |
3 |
25% |
Clinical study results | 2 | 17% |
Disease patterns and progression | 2 | 17% |
Testing and diagnosis research | 1 | 8% |
Patient case studies | 1 | 8% |
Fullin J (2026). [PMID: 41407825](https://pubmed.ncbi.nlm.nih.gov/41407825/). *Leukemia*. [Basic Science / Preclinical]
Kusne Y (2025). [PMID: 40446156](https://pubmed.ncbi.nlm.nih.gov/40446156/). *Endocrine-related cancer*. [Epidemiology / Natural History]
Kubicki T (2025). [PMID: 40776581](https://pubmed.ncbi.nlm.nih.gov/40776581/). *Expert review of hematology*. [Epidemiology / Natural History]
Tesi B (2025). [PMID: 40388595](https://pubmed.ncbi.nlm.nih.gov/40388595/). *Clinical cancer research : an official journal of the American Association for Cancer Research*. [Basic Science / Preclinical]
Shahzad M (2025). [PMID: 39890517](https://pubmed.ncbi.nlm.nih.gov/39890517/). *Clinical lymphoma, myeloma & leukemia*. [Diagnostic / Biomarker]
Nathan DI (2025). [PMID: 40505637](https://pubmed.ncbi.nlm.nih.gov/40505637/). *Acta haematologica*. [Clinical Trial Publication]
Alkhaledi A (2025). [PMID: 41363702](https://pubmed.ncbi.nlm.nih.gov/41363702/). *Cancer reports (Hoboken, N.J.)*. [Case Report / Case Series]
Buckman MA (2025). [PMID: 40913257](https://pubmed.ncbi.nlm.nih.gov/40913257/). *Comprehensive Physiology*. [Review / Meta-Analysis]
El Murr L (2025). [PMID: 41067951](https://pubmed.ncbi.nlm.nih.gov/41067951/). *Bulletin du cancer*. [Clinical Trial Publication]
Naidoo K (2025). [PMID: 40776729](https://pubmed.ncbi.nlm.nih.gov/40776729/). *South African family practice : official journal of the South African Academy of Family Practice/Primary Care*. [Review / Meta-Analysis]