acute myeloid leukemia, inv(3)(q21.3;q26.2)

Acute myeloid leukemia, inv(3)(q21.3;q26.2) is a type of blood cancer that begins in the bone marrow, where new blood cells are made. It is defined by a specific cytogenetic abnormality—an inversion of a portion of chromosome 3. This inversion, known as inv(3)(q21.3;q26.2), means that part of the long arm of chromosome 3 is flipped in orientation. In people with this condition, the change in the structure of the chromosome can lead to the abnormal growth and development of blood cells. Because the leukemia is associated with this particular chromosomal anomaly, it is classified as a distinct subtype of acute myeloid leukemia. Awareness of this genetic change aids medical professionals in understanding how the disease develops and in distinguishing it from other types of blood cancers. While more detailed information about how this inversion leads to the development of leukemia is still being researched, recognition of this abnormality remains key in the overall classification and study of acute myeloid leukemia.

Information about symptoms is currently limited for this condition.

This form of acute myeloid leukemia is defined by the presence of a specific genetic change. The condition arises from a paracentric inversion within chromosome 3, noted as inv(3)(q21.3;q26.2). This genetic rearrangement alters the structure of the chromosome and can affect the behavior of blood cells. Further details on additional genetic or environmental risk factors are currently limited.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.