Acute myeloid leukemia, t(1;11)(q21;q23) is a type of blood cancer characterized by a specific chromosomal abnormality. In this condition, a piece of chromosome 1 (at band q21) swaps places with a piece of chromosome 11 (at band q23). Such rearrangements can lead to changes in the behavior of blood cells, contributing to leukemia. This form of leukemia is known to be linked with fusions between the KMT2A (also known as MLL) and MLLT11 (AF1Q) genes. The fusion of these genes is thought to play a role in the development and progression of the disease. The information available mainly highlights the genetic aspect of the condition.

Information about symptoms is currently limited for this condition.

This condition is caused by a genetic abnormality involving a chromosomal translocation t(1;11)(q21;q23). This abnormality results in the fusion of parts of two genes, KMT2A (MLL) and MLLT11 (AF1Q), which is believed to contribute to the development of leukemia.