Acute myeloid leukemia, t(11;19)(q23.3;p13.3) is a rare subtype of acute myeloid leukemia. It is defined by a specific chromosomal abnormality where part of chromosome 11 is exchanged with part of chromosome 19, leading to a gene fusion between KMT2A (also known as MLL) and MLLT1 (also known as ENL). This condition is identified through the detection of the translocation t(11;19)(q23.3;p13.3) and is part of the broader group of acute myeloid leukemias. The chromosomal change affects how cells grow and divide, which is key to developing this type of leukemia.

Information about common symptoms and signs is currently limited for this condition.

This type of acute myeloid leukemia is caused by a specific chromosomal translocation, t(11;19)(q23.3;p13.3). This abnormal exchange involves the long arm of chromosome 11 and the short arm of chromosome 19 and leads to a fused gene involving KMT2A and MLLT1. This gene fusion plays a role in how cells grow abnormally, contributing to the development of the leukemia.