Acute myeloid leukemia, t(9;11)(p21.3;q23.3) is a type of blood cancer characterized by a specific change in the cells' chromosomes. In this condition, a segment from the short arm of chromosome 9 swaps with a segment from the long arm of chromosome 11. This rearrangement creates a fusion gene called MLLT3-MLL, which plays a key role in the development of the disease. This chromosomal anomaly leads to the abnormal production of white blood cells in the bone marrow, which can interfere with the body’s normal blood cell production. Understanding this genetic change is important for researchers and doctors as it can help in studying the behavior of the disease.

Information about symptoms is currently limited for this condition.

This type of acute myeloid leukemia is caused by a specific chromosomal change. The translocation between parts of chromosome 9 and chromosome 11 leads to the formation of a fusion gene (MLLT3-MLL) that disrupts normal blood cell production and promotes abnormal cell growth. This genetic event is the main cause of the condition.