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Adenoid cystic carcinoma is described in the packet as a malignant tumor arising from epithelial cells. Under the microscope, the tumor cells form cylindrical (cribriform or classic), cordlike (tubular), or solid (basaloid) arrangements. It occurs mostly in the salivary glands, with other primary sites including the lacrimal gland, larynx, and lungs. The packet also lists many site-specific subtypes, such as salivary gland, lacrimal gland, lung, tracheal, laryngeal, and breast forms.
The packet lists no associated genes and no inheritance pattern for adenoid cystic carcinoma, so the genetic basis is not certified here. The definition notes that lymph node metastases are unusual and that hematogenous tumor spread, meaning spread through the bloodstream, is characteristic.
The packet does not certify specific diagnostic tests or criteria. The definition describes the microscopic appearance used to characterize the tumor: cribriform or classic, tubular, and solid basaloid patterns.
Treatment coverage is not certified in this packet, and no foundational therapies or FDA-approved treatments are recorded. Several investigational agents hold orphan drug designation for adenoid cystic carcinoma. Designation is a regulatory status and does not indicate approval, development stage, or availability.
36 trials found
The packet does not certify a natural history or outcome data for this condition. The definition states only that the tumor tends to recur and that spread through the bloodstream is characteristic.
According to ClinicalTrials.gov records in the packet, active clinical trials exist for this condition. They include early-phase and phase 2 studies, some focused on adenoid cystic carcinoma and others on salivary gland cancers more broadly, and the intervention types include drug therapy, biologic therapy, and procedural interventions such as radiotherapy. Active clinical trials for this condition are listed on ClinicalTrials.gov.
Data assembled from 4 of 12 sources · Last updated Nov 5, 2026, 2:48 PM UTC
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Common questions about adenoid cystic carcinoma
AI-curated news mentioning adenoid cystic carcinoma
Updated Oct 19, 2026
Remix Therapeutics is advancing its lead program, REM-422, targeting adenoid cystic carcinoma, a rare cancer with no approved therapies. The company focuses on small molecule medicines that correct RNA splicing errors linked to various serious conditions.
A recent SEER analysis provides updated insights into the demographics, clinical features, and survival rates of patients with adenoid cystic carcinoma. This study compares outcomes in major and minor salivary glands versus non-salivary sites, enhancing understanding of this rare cancer.
A recent case series published on PubMed highlights findings from 26 patients with adenoid cystic carcinoma of the breast. This research contributes to the understanding of this rare breast cancer subtype.
A rare case study highlights the clinical presentation and histopathological evaluation of adenoid cystic carcinoma in the male breast. This research contributes to the understanding of this uncommon malignancy.