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Adenoid cystic carcinoma is classified as a rare malignant neoplasm within the MONDO disease ontology. Multiple anatomic subtypes are recognized in the available dataset, including salivary gland adenoid cystic carcinoma (MONDO:0003175), lung adenoid cystic carcinoma (MONDO:0003181), lacrimal gland adenoid cystic carcinoma (MONDO:0006262), breast adenoid cystic carcinoma (MONDO:0003185), laryngeal adenoid cystic carcinoma (MONDO:0006264), tracheal adenoid cystic carcinoma (MONDO:0006471), pharyngeal adenoid cystic carcinoma (MONDO:0006367), and esophageal, cutaneous, vaginal, cervical, prostate, Bartholin gland, paranasal sinus, and lymph node variants, among others. No structured prevalence data are recorded in this packet.
No structured phenotype or clinical feature data are available in this packet's phenotype field. Clinical manifestations of adenoid cystic carcinoma are not enumerated in the available dataset. The breadth of recognized anatomic subtypes in this packet indicates the condition can arise across multiple organ sites, including the head and neck, thorax, breast, and reproductive tract, though specific symptom data are not present in this knowledge packet.
No causative genes or associated molecular data are recorded in this packet's known genes field. No inheritance pattern is specified in the packet. Adenoid cystic carcinoma is a malignant neoplasm; no germline genetic causation or molecular driver data are populated in the available dataset. No ClinGen gene validity records and no ClinVar variant data are present in this packet.
No structured diagnostic criteria or clinical diagnostic field data are present in this packet. Information about diagnostic workup, histopathologic criteria, or clinical classification frameworks for adenoid cystic carcinoma is not available from the packet fields accessed in this dataset. The anatomic subtype structure documented in the MONDO ontology provides site-based disease classification.
No approved treatments or foundational therapies are recorded in this packet's treatment fields. No FDA-approved agents are listed for adenoid cystic carcinoma in the available data. Ten clinical trials related to this condition are documented in ClinicalTrials.gov data within this packet, including a study of docetaxel and SX-682 in recurrent or metastatic head and neck carcinoma and salivary gland carcinoma (NCT07667400) and a study of talimogene laherparepvec and nivolumab in refractory lymphoma settings (NCT02978625). ClinicalTrials.gov is the authoritative source for current enrollment and eligibility information.
35 trials found
No structured natural history or prognosis data are present in this packet. Disease course and outcome information for adenoid cystic carcinoma is not available from the fields accessible in this dataset. No natural history field data were populated in the available knowledge packet.
Ten clinical trials related to adenoid cystic carcinoma are recorded in ClinicalTrials.gov data within this packet. Active or planned investigations include a first-in-human multicenter dose-escalation study (NCT07755397, recruiting) and combination therapy trials targeting recurrent and metastatic disease. ClinicalTrials.gov and the EU Clinical Trials Register are the authoritative sources for current research enrollment information for this condition.
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 10:03 PM UTC
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Common questions about adenoid cystic carcinoma
AI-curated news mentioning adenoid cystic carcinoma
Updated Jun 12, 2026
A recent case series published on PubMed highlights findings from 26 patients with adenoid cystic carcinoma of the breast. This research contributes to the understanding of this rare breast cancer subtype.
A rare case study highlights the clinical presentation and histopathological evaluation of adenoid cystic carcinoma in the male breast. This research contributes to the understanding of this uncommon malignancy.
A recent study highlights an uncommon presentation of adenoid cystic carcinoma in the trachea, contributing to the understanding of this rare malignancy. The findings may inform future research and clinical approaches to this disease.