Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A germ cell tumor that occurs during adulthood.
Biomarker and diagnostic research for adult germ cell tumor has been reported in the published literature.
67 clinical trials registered, 26 recruiting. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 4 PHASE3, 24 PHASE2, 13 PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT06937866](https://clinicaltrials.gov/study/NCT06937866) |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 9:44 PM UTC
Common questions about adult germ cell tumor
Maintenance Zanzalintinib With Etoposide After HDCT in GCT |
PHASE1 |
Indiana University |
RECRUITING |
[NCT05092451](https://clinicaltrials.gov/study/NCT05092451) | Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances | PHASE1 | M.D. Anderson Cancer Center | RECRUITING |
[NCT05705687](https://clinicaltrials.gov/study/NCT05705687) | Validation of a Treatment Algorithm for Poor-Risk NSGCTnon Seminomatous Germ-cell Tumors | NA | Gustave Roussy, Cancer Campus, Grand Paris | RECRUITING |
[NCT07121322](https://clinicaltrials.gov/study/NCT07121322) | Dornase Alfa and Cisplatin in Refractory Germ Cell Cancer. | PHASE2 | National Cancer Institute, Slovakia | RECRUITING |
[NCT02582697](https://clinicaltrials.gov/study/NCT02582697) | Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours | PHASE3 | University of Sydney | RECRUITING |
429 publications have been identified in PubMed for adult germ cell tumor. Research spans Epidemiology / Natural History (21%), Case Report / Case Series (21%), and Basic Science / Preclinical (17%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 90 | 21% |
Patient case studies | 88 | 21% |
Laboratory research | 74 | 17% |
Research summaries | 70 | 16% |
Clinical study results | 52 | 12% |
Testing and diagnosis research | 41 | 10% |
Other research | 9 | 2% |
New treatment approaches | 5 | 1% |
Noto Y (2026). [PMID: 41736172](https://pubmed.ncbi.nlm.nih.gov/41736172/). *Pathol Int*. [Case Report / Case Series]
Rieg A (2026). [PMID: 41386269](https://pubmed.ncbi.nlm.nih.gov/41386269/). *Interdisciplinary cardiovascular and thoracic surgery*. [Case Report / Case Series]
Kidess M (2026). [PMID: 42004047](https://pubmed.ncbi.nlm.nih.gov/42004047/). *BJUI Compass*. [Epidemiology / Natural History]
Hammami MB (2026). [PMID: 41922334](https://pubmed.ncbi.nlm.nih.gov/41922334/). *Nat Commun*. [Basic Science / Preclinical]
Bagrecha M (2026). [PMID: 41741123](https://pubmed.ncbi.nlm.nih.gov/41741123/). *BMJ case reports*. [Diagnostic / Biomarker]
Omameuda T (2026). [PMID: 41991407](https://pubmed.ncbi.nlm.nih.gov/41991407/). *Transplant Proc*. [Review / Meta-Analysis]
Strauch A (2026). [PMID: 41111273](https://pubmed.ncbi.nlm.nih.gov/41111273/). *BJU international*. [Clinical Trial Publication]
Wu Z (2026). [PMID: 41485106](https://pubmed.ncbi.nlm.nih.gov/41485106/). *J Natl Cancer Inst*. [Epidemiology / Natural History]
Zeng J (2026). [PMID: 41689870](https://pubmed.ncbi.nlm.nih.gov/41689870/). *Urol Oncol*. [Clinical Trial Publication]
Sarade M (2026). [PMID: 41969539](https://pubmed.ncbi.nlm.nih.gov/41969539/). *Ecancermedicalscience*. [Epidemiology / Natural History]
AI-curated news mentioning adult germ cell tumor
Updated Jul 10, 2026
A case study highlights the diagnostic challenges of primary high-grade intraperitoneal sarcoma in an 8-year-old girl, initially misidentified as a germ cell tumor. This report emphasizes the need for careful differential diagnosis in pediatric oncology.
A new study identifies risk factors and causes of early death in germ cell tumors, providing critical insights for improving patient outcomes. This research highlights the need for targeted interventions in this rare cancer population.
A new study provides the first description of an orthotopically located spontaneously ruptured non-seminomatous metastatic germ cell tumor. This research contributes to the understanding of rare tumor presentations and may inform future clinical approaches.
Tarik's story highlights the challenges faced by individuals with rare germ cell tumors and hypopituitarism, emphasizing the importance of visibility for rare diseases. His journey serves as a reminder of the resilience and support within the rare disease community.