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A pineoblastoma occurring in adults.
Biomarker and diagnostic research for adult pineoblastoma has been reported in the published literature.
8 clinical trials registered, 6 recruiting. Interventions under study include drug therapy, biologic therapy, procedural interventions, and other interventions. Pipeline includes 5 PHASE1, 2 EARLY_PHASE1. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT07087002](https://clinicaltrials.gov/study/NCT07087002) |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 1:16 AM UTC
Common questions about adult pineoblastoma
GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults |
PHASE1 |
Stanford University |
RECRUITING |
[NCT03500991](https://clinicaltrials.gov/study/NCT03500991) | HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors | PHASE1 | Seattle Children's Hospital | ACTIVE_NOT_RECRUITING |
[NCT07017816](https://clinicaltrials.gov/study/NCT07017816) | A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. | EARLY_PHASE1 | Children's National Research Institute | RECRUITING |
[NCT03382158](https://clinicaltrials.gov/study/NCT03382158) | International PPB/DICER1 Registry | — | Children's Hospitals and Clinics of Minnesota | UNKNOWN |
[NCT04185038](https://clinicaltrials.gov/study/NCT04185038) | Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors | PHASE1 | Seattle Children's Hospital | RECRUITING |
82 publications have been identified in PubMed for adult pineoblastoma. Research spans Case Report / Case Series (28%), Review / Meta-Analysis (24%), and Basic Science / Preclinical (16%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 22 | 28% |
Research summaries | 19 | 24% |
Laboratory research | 13 | 16% |
Clinical study results | 11 | 14% |
Disease patterns and progression | 10 | 13% |
Testing and diagnosis research | 4 | 5% |
New treatment approaches | 1 | 1% |
Gatz SA (2026). [PMID: 41591981](https://pubmed.ncbi.nlm.nih.gov/41591981/). *Clin Cancer Res*. [Clinical Trial Publication]
Vasiljevic A (2026). [PMID: 42115456](https://pubmed.ncbi.nlm.nih.gov/42115456/). *Adv Tech Stand Neurosurg*. [Review / Meta-Analysis]
Babu S (2026). [PMID: 42055031](https://pubmed.ncbi.nlm.nih.gov/42055031/). *J Natl Compr Canc Netw*. [Epidemiology / Natural History]
Shukla V (2026). [PMID: 42087668](https://pubmed.ncbi.nlm.nih.gov/42087668/). *Neurol India*. [Case Report / Case Series]
Pasquinelli E (2026). [PMID: 42058762](https://pubmed.ncbi.nlm.nih.gov/42058762/). *Neurooncol Adv*. [Review / Meta-Analysis]
Troy C (2026). [PMID: 42234250](https://pubmed.ncbi.nlm.nih.gov/42234250/). *J Neurooncol*. [Clinical Trial Publication]
Hogg FRA (2026). [PMID: 41871435](https://pubmed.ncbi.nlm.nih.gov/41871435/). *J Neurosurg Pediatr*. [Basic Science / Preclinical]
Szathmari A (2026). [PMID: 42115466](https://pubmed.ncbi.nlm.nih.gov/42115466/). *Adv Tech Stand Neurosurg*. [Epidemiology / Natural History]
Tanguy R (2026). [PMID: 42115465](https://pubmed.ncbi.nlm.nih.gov/42115465/). *Adv Tech Stand Neurosurg*. [Review / Meta-Analysis]
Vitulli F (2026). [PMID: 41832330](https://pubmed.ncbi.nlm.nih.gov/41832330/). *Childs Nerv Syst*. [Review / Meta-Analysis]