agammaglobulinemia 10, autosomal dominant

Agammaglobulinemia 10, autosomal dominant is a condition that usually begins in early childhood. People with this condition experience recurrent viral and bacterial infections affecting different parts of the body, especially the sinopulmonary system. Laboratory tests often reveal low or absent B cells and low levels of immunoglobulins. This condition may also cause adverse reactions to certain vaccinations, such as the polio vaccine. Early recognition and diagnosis are important for managing infections and other complications effectively.

People with agammaglobulinemia 10 may have repeated infections of the respiratory system, along with other viral and bacterial infections. These symptoms usually start in early childhood and can affect various organs.

This condition is caused by genetic changes and is inherited in an autosomal dominant manner. It is associated with changes in the SPI1 gene. The condition leads to problems with B cell production and a reduction or absence of immunoglobulins in the blood.

Treatment for agammaglobulinemia 10 often includes replacement immunoglobulin (Ig) therapy, which helps to provide the antibodies the body is missing. In some cases, hematopoietic stem cell transplantation has also been reported. These treatments aim to reduce the risk of infections and manage the condition over time.

With early diagnosis and proper treatment, people with this condition can manage symptoms and reduce the frequency of infections. However, the outlook depends on individual factors and the severity of immune deficiency. Ongoing medical care is important for overall health.

Information about current research for agammaglobulinemia 10, autosomal dominant is currently limited for this condition.