Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A carcinoma that arises from glandular epithelial cells of the hepatopancreatic ampulla
Biomarker and diagnostic research for ampulla of vater adenocarcinoma has been reported in the published literature.
7 clinical trials registered, 4 recruiting. Interventions under study include other interventions, drug therapy, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE4, 1 PHASE3, 1 PHASE2. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT02757859](https://clinicaltrials.gov/study/NCT02757859) |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 2:22 PM UTC
WASH Trial: Intraoperative Lavage as a Treatment for Pancreatic Cancer |
NA |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
UNKNOWN |
[NCT07282912](https://clinicaltrials.gov/study/NCT07282912) | Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels | PHASE2 | Yale University | RECRUITING |
[NCT06068023](https://clinicaltrials.gov/study/NCT06068023) | The ADAPTA Study: ADjuvant chemotherAPy After Curative Intent resecTion of Ampullary Cancer. | — | Fondazione Poliambulanza Istituto Ospedaliero | UNKNOWN |
[NCT07262957](https://clinicaltrials.gov/study/NCT07262957) | Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA) | PHASE4 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | RECRUITING |
[NCT05116072](https://clinicaltrials.gov/study/NCT05116072) | Efficacy and Safety of TPIAT for Resectable Adenocarcinoma of the Pancreas Region at High Risk of Postoperative Fistula | PHASE1 | University Hospital, Lille | UNKNOWN |
126 publications have been identified in PubMed for ampulla of vater adenocarcinoma. Research spans Case Report / Case Series (28%), Clinical Trial Publication (25%), and Epidemiology / Natural History (18%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 35 | 28% |
Clinical study results | 32 | 25% |
Disease patterns and progression | 23 | 18% |
Laboratory research | 15 | 12% |
Testing and diagnosis research | 13 | 10% |
Research summaries | 3 | 2% |
New treatment approaches | 3 | 2% |
Other research | 2 | 2% |
Wonglhow J (2026). [PMID: 42266838](https://pubmed.ncbi.nlm.nih.gov/42266838/). *Cancer Manag Res*. [Clinical Trial Publication]
Bhandare MS (2026). [PMID: 38939924](https://pubmed.ncbi.nlm.nih.gov/38939924/). *Annals of surgery*. [Diagnostic / Biomarker]
Das B (2026). [PMID: 42160230](https://pubmed.ncbi.nlm.nih.gov/42160230/). *Eur Surg Res*. [Clinical Trial Publication]
Epitropoulos F (2026). [PMID: 41809955](https://pubmed.ncbi.nlm.nih.gov/41809955/). *European journal of case reports in internal medicine*. [Diagnostic / Biomarker]
Hoang TM (2026). [PMID: 42130863](https://pubmed.ncbi.nlm.nih.gov/42130863/). *Case Rep Oncol*. [Case Report / Case Series]
Schouten TJ (2026). [PMID: 41662856](https://pubmed.ncbi.nlm.nih.gov/41662856/). *Lancet Gastroenterol Hepatol*. [Clinical Trial Publication]
Antonakis PT (2026). [PMID: 41951263](https://pubmed.ncbi.nlm.nih.gov/41951263/). *BMJ Case Rep*. [Case Report / Case Series]
Suto K (2026). [PMID: 41982569](https://pubmed.ncbi.nlm.nih.gov/41982569/). *Cureus*. [Case Report / Case Series]
İnce MM (2026). [PMID: 41753208](https://pubmed.ncbi.nlm.nih.gov/41753208/). *J Clin Med*. [Epidemiology / Natural History]
Pellegrini R (2026). [PMID: 41821156](https://pubmed.ncbi.nlm.nih.gov/41821156/). *Journal of hepato-biliary-pancreatic sciences*. [Clinical Trial Publication]