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A carcinoma that arises from epithelial cells of the anal canal
Features include: Anal canal squamous carcinoma.
Biomarker and diagnostic research for anal canal carcinoma has been reported in the published literature.
14 clinical trials registered, 1 recruiting. Interventions under study include other interventions, procedural interventions, drug therapy, and biologic therapy. Pipeline includes 2 PHASE3, 8 PHASE2, 1 PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05040815](https://clinicaltrials.gov/study/NCT05040815) |
Data assembled from 6 of 12 sources · Last updated Sep 19, 2026, 3:02 AM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Inguinal Node Sparing Radiotherapy For Patients With Early Stage Anal Cancer |
PHASE2 |
AHS Cancer Control Alberta |
RECRUITING |
46 publications have been identified in PubMed for anal canal carcinoma. Research spans Case Report / Case Series (43%), Review / Meta-Analysis (20%), and Epidemiology / Natural History (20%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 20 | 43% |
Research summaries | 9 | 20% |
Disease patterns and progression | 9 | 20% |
Testing and diagnosis research | 4 | 9% |
Clinical study results | 3 | 7% |
Other research | 1 | 2% |
Ozawa Y (2026). [PMID: 41589233](https://pubmed.ncbi.nlm.nih.gov/41589233/). *Int Cancer Conf J*. [Other]
Lin L (2026). [PMID: 41929384](https://pubmed.ncbi.nlm.nih.gov/41929384/). *Front Surg*. [Case Report / Case Series]
Niwa K (2026). [PMID: 41904746](https://pubmed.ncbi.nlm.nih.gov/41904746/). *Int J Clin Oncol*. [Epidemiology / Natural History]
Kohyama A (2026). [PMID: 41623599](https://pubmed.ncbi.nlm.nih.gov/41623599/). *J Anus Rectum Colon*. [Epidemiology / Natural History]
Medical Administration Department, National Health Commission of the People′s Republic of China (2026). [PMID: 41667920](https://pubmed.ncbi.nlm.nih.gov/41667920/). *Zhonghua Wai Ke Za Zhi*. [Review / Meta-Analysis]
Marcon LR (2026). [PMID: 41534233](https://pubmed.ncbi.nlm.nih.gov/41534233/). *Explore (New York, N.Y.)*. [Case Report / Case Series]
Department of Medical Administration, National Health Commission (2026). [PMID: 41566174](https://pubmed.ncbi.nlm.nih.gov/41566174/). *Zhonghua Wei Chang Wai Ke Za Zhi*. [Review / Meta-Analysis]
Tomaciello M (2026). [PMID: 41708358](https://pubmed.ncbi.nlm.nih.gov/41708358/). *Clinical colorectal cancer*. [Case Report / Case Series]
Yamada K (2026). [PMID: 41452529](https://pubmed.ncbi.nlm.nih.gov/41452529/). *International journal of clinical oncology*. [Case Report / Case Series]
Nishimura H (2026). [PMID: 41913825](https://pubmed.ncbi.nlm.nih.gov/41913825/). *Cureus*. [Case Report / Case Series]
AI-curated news mentioning anal canal carcinoma
Updated Aug 31, 2026
Recent research explores therapeutic approaches for metastatic or unresectable recurrent anal canal cancer, highlighting emerging perspectives in treatment strategies. This study contributes to the understanding of this rare cancer's management.
A retrospective cohort study highlights the prognostic significance of systemic inflammatory indices in patients with squamous cell carcinoma of the anal canal. This research may inform future clinical assessments and treatment strategies.
A recent study provides a detailed clinicopathologic characterization of primary anal canal mucosal melanomas, enhancing understanding of this rare cancer type. The findings may inform future research and treatment strategies.