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anaplastic ganglioglioma (AGNG) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

anaplastic ganglioglioma

MONDO:0016734

Also known as:AGNG

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Overview

A WHO grade III neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and anaplastic glial cells. The anaplastic changes in the glial component and high MIB-1 and TP53 labeling indices may indicate aggressive behavior. However, the correlation of histological anaplasia with clinical outcome is inconsistent. (Adapted from WHO)

Clinical Trials2 registered

ResearchLimited published research (5 articles)

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

2 clinical trials registered. Interventions under study include drug therapy and procedural interventions. Pipeline includes 1 PHASE4, 1 PHASE2. Research is sponsored by a mix of industry and academic institutions.

5 publications have been identified in PubMed for anaplastic ganglioglioma. Research spans Case Report / Case Series (60%), Clinical Trial Publication (20%), and Epidemiology / Natural History (20%).

Recent Publications

Rubisoier L (2026). [PMID: 41716879](https://pubmed.ncbi.nlm.nih.gov/41716879/). *Brain Spine*. [Case Report / Case Series]
Umana GE (2025). [PMID: 39246067](https://pubmed.ncbi.nlm.nih.gov/39246067/). *Br J Neurosurg*. [Case Report / Case Series]
Geoerger B (2025). [PMID: 41458923](https://pubmed.ncbi.nlm.nih.gov/41458923/). *Neurooncol Pract*. [Clinical Trial Publication]
Vizcaino MA (2024). [PMID: 38699943](https://pubmed.ncbi.nlm.nih.gov/38699943/). *J Neuropathol Exp Neurol*. [Case Report / Case Series]
Guo LA (2024). [PMID: 38825904](https://pubmed.ncbi.nlm.nih.gov/38825904/). *Zhonghua Bing Li Xue Za Zhi*. [Epidemiology / Natural History]

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 5:50 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:251957

GARD

Genetic and Rare Diseases Info Center

GARD:10639

Questions for Your Care Team

→Are any of the 2 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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anaplastic ganglioglioma

Overview

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team