Swelling involving the deep dermis, subcutaneous, or submucosal tissues, representing localized edema. Angioedema often occurs in the face, lips, tongue, and larynx.
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Documentation on angioedema is limited due to its complex nature and the fact that it affects a relatively small population. The variability in triggers and symptoms makes systematic clinical studies challenging. Additionally, the lack of identified genes and inheritance patterns contributes to the difficulty in characterizing the condition comprehensively. Despite these challenges, ongoing research aims to enhance our understanding and management of angioedema.
To effectively manage angioedema, consider consulting with an allergist or immunologist who specializes in allergic conditions and angioedema. These specialists can provide tailored treatment plans and management strategies. Additionally, you may find resources through the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov, which can offer guidance on navigating care options. Participating in clinical trials may also provide access to new therapies and contribute to ongoing research efforts.
There are currently four FDA-approved orphan drugs for angioedema: C1 esterase inhibitor (human), ecallantide, icatibant, and lanadelumab-flyo. Additionally, there are 49 active clinical trials exploring various aspects of angioedema management and treatment options. For more information on these trials, you can visit ClinicalTrials.gov and search for angioedema: https://clinicaltrials.gov/search?cond=angioedema.
Actionable guidance for navigating care for angioedema
To effectively manage angioedema, consider consulting with an allergist or immunologist who specializes in allergic conditions and angioedema. These specialists can provide tailored treatment plans and management strategies. Additionally, you may find resources through the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov, which can offer guidance on navigating care options. Participating in clinical trials may also provide access to new therapies and contribute to ongoing research efforts.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Consider asking your healthcare providers these condition-specific questions
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Organizations with approved therapies for this disease
No approved therapies yet
Research is ongoing — 5 companies have orphan drug designations for this disease
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