Anterior ischemic optic neuropathy (AION) is an eye disease characterized by infarction of the optic disk leading to vision loss. It can be nonarteritic (nonarteritic anterior ischemic optic neuropath...
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
The documentation on anterior ischemic optic neuropathy is limited due to its relatively rare occurrence and the complexity of its clinical presentation. As AION affects fewer individuals, systematic clinical studies have been sparse, making comprehensive data collection challenging. Additionally, the lack of identified genetic factors and established inheritance patterns further complicates the understanding of this condition.
To navigate your journey with anterior ischemic optic neuropathy, consider consulting a neuro-ophthalmologist who specializes in optic nerve disorders. They can provide targeted insights and management strategies. Additionally, you can explore opportunities to participate in clinical trials, which may offer access to novel treatments. For more resources, visit ClinicalTrials.gov for ongoing studies. Although no specific patient organizations are identified, connecting with general rare disease organizations like NORD (rarediseases.org) can provide support and information.
There are currently 12 active clinical trials investigating various aspects of anterior ischemic optic neuropathy. Notably, several orphan drugs are in development, including a 19 amino acid synthetic peptide NOS-enhancer, Brimonidine, NP-CSIC002, and a synthetic double-stranded siRNA oligonucleotide directed against p53 mRNA. For more information on these trials, you can visit ClinicalTrials.gov and search for anterior ischemic optic neuropathy.
Actionable guidance for navigating care for anterior ischemic optic neuropathy
To navigate your journey with anterior ischemic optic neuropathy, consider consulting a neuro-ophthalmologist who specializes in optic nerve disorders. They can provide targeted insights and management strategies. Additionally, you can explore opportunities to participate in clinical trials, which may offer access to novel treatments. For more resources, visit ClinicalTrials.gov for ongoing studies. Although no specific patient organizations are identified, connecting with general rare disease organizations like NORD (rarediseases.org) can provide support and information.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Consider asking your healthcare providers these condition-specific questions
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Organizations with approved therapies for this disease
No approved therapies yet
Research is ongoing — 4 companies have orphan drug designations for this disease
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