An anterior ischemic neuropathy that is the cause of vision loss that occurs in temporal arteritis (aka giant cell arteritis)
Comprehensive, easy-to-understand information about this condition
How we create this content →The limited documentation surrounding arteritic anterior ischemic optic neuropathy is primarily due to its association with temporal arteritis, a condition that affects a relatively small population. Consequently, the number of systematic clinical studies focused on AAION is limited. Additionally, the variability in clinical presentation and the overlap with other optic neuropathies contribute to the challenges in establishing a comprehensive understanding of this condition.
To navigate your care, it is essential to seek out specialists experienced in managing arteritic anterior ischemic optic neuropathy, such as neuro-ophthalmologists or rheumatologists who specialize in temporal arteritis. Although there are currently no identified patient organizations, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information. Additionally, consider participating in clinical trials to contribute to ongoing research and potentially access new therapies.
There are currently four active clinical trials investigating treatment options for arteritic anterior ischemic optic neuropathy. Notable orphan drugs under development include a 19 amino acid synthetic peptide NOS-enhancer, Brimonidine, NP-CSIC002, and a synthetic double-stranded siRNA oligonucleotide directed against p53 mRNA. For more information on these trials, you can visit the ClinicalTrials.gov search page: https://clinicaltrials.gov/search?cond=arteritic%20anterior%20ischemic%20optic%20neuropathy.
Actionable guidance for navigating care for arteritic anterior ischemic optic neuropathy
To navigate your care, it is essential to seek out specialists experienced in managing arteritic anterior ischemic optic neuropathy, such as neuro-ophthalmologists or rheumatologists who specialize in temporal arteritis. Although there are currently no identified patient organizations, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information. Additionally, consider participating in clinical trials to contribute to ongoing research and potentially access new therapies.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The limited documentation surrounding arteritic anterior ischemic optic neuropathy is primarily due to its association with temporal arteritis, a condition that affects a relatively small population. Consequently, the number of systematic clinical studies focused on AAION is limited. Additionally, the variability in clinical presentation and the overlap with other optic neuropathies contribute to the challenges in establishing a comprehensive understanding of this condition.
To navigate your care, it is essential to seek out specialists experienced in managing arteritic anterior ischemic optic neuropathy, such as neuro-ophthalmologists or rheumatologists who specialize in temporal arteritis. Although there are currently no identified patient organizations, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information. Additionally, consider participating in clinical trials to contribute to ongoing research and potentially access new therapies.
There are currently four active clinical trials investigating treatment options for arteritic anterior ischemic optic neuropathy. Notable orphan drugs under development include a 19 amino acid synthetic peptide NOS-enhancer, Brimonidine, NP-CSIC002, and a synthetic double-stranded siRNA oligonucleotide directed against p53 mRNA. For more information on these trials, you can visit the ClinicalTrials.gov search page: https://clinicaltrials.gov/search?cond=arteritic%20anterior%20ischemic%20optic%20neuropathy.
Actionable guidance for navigating care for arteritic anterior ischemic optic neuropathy
To navigate your care, it is essential to seek out specialists experienced in managing arteritic anterior ischemic optic neuropathy, such as neuro-ophthalmologists or rheumatologists who specialize in temporal arteritis. Although there are currently no identified patient organizations, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information. Additionally, consider participating in clinical trials to contribute to ongoing research and potentially access new therapies.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The limited documentation surrounding arteritic anterior ischemic optic neuropathy is primarily due to its association with temporal arteritis, a condition that affects a relatively small population. Consequently, the number of systematic clinical studies focused on AAION is limited. Additionally, the variability in clinical presentation and the overlap with other optic neuropathies contribute to the challenges in establishing a comprehensive understanding of this condition.
To navigate your care, it is essential to seek out specialists experienced in managing arteritic anterior ischemic optic neuropathy, such as neuro-ophthalmologists or rheumatologists who specialize in temporal arteritis. Although there are currently no identified patient organizations, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information. Additionally, consider participating in clinical trials to contribute to ongoing research and potentially access new therapies.
There are currently four active clinical trials investigating treatment options for arteritic anterior ischemic optic neuropathy. Notable orphan drugs under development include a 19 amino acid synthetic peptide NOS-enhancer, Brimonidine, NP-CSIC002, and a synthetic double-stranded siRNA oligonucleotide directed against p53 mRNA. For more information on these trials, you can visit the ClinicalTrials.gov search page: https://clinicaltrials.gov/search?cond=arteritic%20anterior%20ischemic%20optic%20neuropathy.
Actionable guidance for navigating care for arteritic anterior ischemic optic neuropathy
To navigate your care, it is essential to seek out specialists experienced in managing arteritic anterior ischemic optic neuropathy, such as neuro-ophthalmologists or rheumatologists who specialize in temporal arteritis. Although there are currently no identified patient organizations, resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov can provide valuable information. Additionally, consider participating in clinical trials to contribute to ongoing research and potentially access new therapies.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Organizations with approved therapies for this disease
No approved therapies yet
Research is ongoing — 1 company has orphan drug designations for this disease
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