Lungs and breathing

6

Difficulty breathing (respiratory insufficiency), Lung scarring (pulmonary fibrosis), Abnormal lung tissue (abnormal pulmonary interstitial morphology)

Skin

4

Lack of skin elasticity, Skin rash, Pruritus

Muscles

3

Muscle weakness, Myalgia, Low muscle tone (hypotonia)

Heart and blood vessels

3

Chest pain, Aortic regurgitation, High blood pressure in lung arteries (pulmonary arterial hypertension)

Bones and joints

3

Joint inflammation (arthritis), Arthralgia, Joint dislocation

Blood and immune system

2

Autoimmunity, Recurrent respiratory infections

Arms and legs

2

Mechanic's hands, Hiker's feet

Metabolism

1

Fever

Voice

1

Abnormality of the voice

Digestive system

1

Difficulty swallowing (dysphagia)

Brain and nerves

1

Difficulty swallowing (dysphagia)

Neoplasm

1

Neoplasm

[NCT05984394](https://clinicaltrials.gov/study/NCT05984394)

Evaluation of Antigen-specific T Cells in Patients With Antisynthetase Syndrome and Interstitial Lung Disease

—

Central Hospital, Nancy, France

UNKNOWN

[NCT06613490](https://clinicaltrials.gov/study/NCT06613490)

An Exploratory Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Antisynthetase Antibody Syndrome and Rheumatoid Arthritis

EARLY_PHASE1

The First Affiliated Hospital with Nanjing Medical University

RECRUITING

[NCT07391605](https://clinicaltrials.gov/study/NCT07391605)

Descartes-08 in Autoantibody Myositis

PHASE2

Cartesian Therapeutics

UNKNOWN

[NCT05832034](https://clinicaltrials.gov/study/NCT05832034)

Add-on Intravenous Immunoglobulins in Early Myositis

PHASE2

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

ACTIVE_NOT_RECRUITING