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A rare congenital heart defect characterized by the complete failure of the aortic valve to open. It is manifested during infancy with cyanosis, dyspnea, and rapidly progressing heart failure.
Biomarker and diagnostic research for aortic valve atresia has been reported in the published literature.
No clinical trials have been registered for aortic valve atresia.
172 publications have been identified in PubMed for aortic valve atresia. Kisho has analyzed 95 by research type. Research spans Review / Meta-Analysis (26%), Clinical Trial Publication (22%), and Epidemiology / Natural History (16%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 25 | 26% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 4:48 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Clinical study results
21 |
22% |
Disease patterns and progression | 15 | 16% |
Laboratory research | 11 | 12% |
Other research | 10 | 11% |
Patient case studies | 9 | 9% |
Testing and diagnosis research | 4 | 4% |
Rajput FA (2026). [PMID: 30725821](https://pubmed.ncbi.nlm.nih.gov/30725821/). *Unknown Journal*. [Clinical Trial Publication]
Tokioka M (2026). [PMID: 42027527](https://pubmed.ncbi.nlm.nih.gov/42027527/). *Ann Thorac Surg Short Rep*. [Case Report / Case Series]
Zhou M (2026). [PMID: 40972881](https://pubmed.ncbi.nlm.nih.gov/40972881/). *Biochim Biophys Acta Mol Basis Dis*. [Basic Science / Preclinical]
Shah AH (2026). [PMID: 41309020](https://pubmed.ncbi.nlm.nih.gov/41309020/). *Am J Cardiol*. [Review / Meta-Analysis]
Saleh D (2026). [PMID: 40675238](https://pubmed.ncbi.nlm.nih.gov/40675238/). *Ann Thorac Surg*. [Epidemiology / Natural History]
Šarkinas L (2026). [PMID: 42075661](https://pubmed.ncbi.nlm.nih.gov/42075661/). *Medicina (Kaunas)*. [Diagnostic / Biomarker]
Sylivris A (2025). [PMID: 39652208](https://pubmed.ncbi.nlm.nih.gov/39652208/). *Int J Cardiovasc Imaging*. [Review / Meta-Analysis]
Gialamas I (2025). [PMID: 40283481](https://pubmed.ncbi.nlm.nih.gov/40283481/). *J Clin Med*. [Review / Meta-Analysis]
Paolisso P (2025). [PMID: 41390096](https://pubmed.ncbi.nlm.nih.gov/41390096/). *Can J Cardiol*. [Review / Meta-Analysis]
Zhu M (2025). [PMID: 40934971](https://pubmed.ncbi.nlm.nih.gov/40934971/). *J Adv Res*. [Basic Science / Preclinical]