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atypical childhood epilepsy with centrotemporal spikes - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

atypical childhood epilepsy with centrotemporal spikes

MONDO:0100020

Also known as:atonic-benign childhood epilepsy with centrotemporal spikesatypical benign partial epilepsy of childhoodpseudo-Lennox syndrome

Overview

A childhood-onset epilepsy that is characterized by frequent seizures of multiple types, including nocturnal focal motor and fronto-parietal opercular seizures, and daytime focal motor seizures with negative myoclonus and atypical absence seizures. Centrotemporal sharp waves are seen on EEG. During the phase of the epilepsy when seizures are frequent, neuropsychological deficits and motor impairment may be present. These deficits improve when seizures remit.

Diagnosis

Biomarker and diagnostic research for atypical childhood epilepsy with centrotemporal spikes has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for atypical childhood epilepsy with centrotemporal spikes.

92 publications have been identified in PubMed for atypical childhood epilepsy with centrotemporal spikes. Research spans Basic Science / Preclinical (59%), Clinical Trial Publication (16%), and Epidemiology / Natural History (13%).

Research Type	Count	% of Total
Laboratory research	44	59%

Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 9:42 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

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atypical childhood epilepsy with centrotemporal spikes

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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