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cryptogenic late-onset epileptic spasms - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

cryptogenic late-onset epileptic spasms

MONDO:0015585

Also known as:late-onset infantile spasms

Overview

Cryptogenic late-onset epileptic spasms is a rare epilepsy syndrome characterized by late-onset (after 1 year old) epileptic spasms that occur in clusters, associated with tonic seizures, atypical absences and cognitive deterioration. Language difficulties and behavior problems are frequently present. EEG is characterized by a temporal, or temporofrontal, slow wave or spike focus combined with synchronous spike-waves and no hypsarrhythmia or background activity.

ResearchLimited published research (1 article)

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for cryptogenic late-onset epileptic spasms.

1 publication has been identified in PubMed for cryptogenic late-onset epileptic spasms. Research spans Clinical Trial Publication (100%).

Recent Publications

Ran Y (2025). [PMID: 41143936](https://pubmed.ncbi.nlm.nih.gov/41143936/). *Neurology and therapy*. [Clinical Trial Publication]

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 3:31 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:163708

GARD

Genetic and Rare Diseases Info Center

GARD:20050

Questions for Your Care Team

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cryptogenic late-onset epileptic spasms

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team