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An inherited or acquired peripheral neuropathy affecting the autonomic nervous system. It results in disruption of the involuntary body functions. Inherited causes include Fabry disease and porphyrias. Acquired causes include diabetes, uremia, hepatic disorders, vitamin deficiencies, toxins, and drug toxicities.
Biomarker and diagnostic research for autonomic neuropathy has been reported in the published literature.
14 clinical trials registered, 4 recruiting. Interventions under study include drug therapy, other interventions, and medical devices. Pipeline includes 2 PHASE4, 2 PHASE2, 1 NA. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT03920774](https://clinicaltrials.gov/study/NCT03920774) |
Data assembled from 3 of 12 sources · Last updated Oct 3, 2026, 8:49 AM UTC
The Natural History of Familial Dysautonomia |
— |
NYU Langone Health |
RECRUITING |
[NCT01793168](https://clinicaltrials.gov/study/NCT01793168) | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford | — | Sanford Health | RECRUITING |
[NCT06906081](https://clinicaltrials.gov/study/NCT06906081) | Finerenone Treatment for Diabetic Cardiovascular Autonomic Neuropathy: the FibroCAN Study | PHASE2 | Peter Rossing | RECRUITING |
[NCT04310644](https://clinicaltrials.gov/study/NCT04310644) | Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry | — | RWTH Aachen University | RECRUITING |
285 publications have been identified in PubMed for autonomic neuropathy. Kisho has analyzed 206 by research type. Research spans Review / Meta-Analysis (36%), Epidemiology / Natural History (20%), and Basic Science / Preclinical (17%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 75 | 36% |
Disease patterns and progression | 41 | 20% |
Laboratory research | 34 | 17% |
Clinical study results | 29 | 14% |
Testing and diagnosis research | 13 | 6% |
Patient case studies | 7 | 3% |
Other research | 5 | 2% |
New treatment approaches | 2 | 1% |
Bilgin Badur N (2026). [PMID: 29494041](https://pubmed.ncbi.nlm.nih.gov/29494041/). *Unknown Journal*. [Other]
Yuba T (2026). [PMID: 42052783](https://pubmed.ncbi.nlm.nih.gov/42052783/). *Rev Neurol*. [Review / Meta-Analysis]
Rebelos E (2026). [PMID: 38414376](https://pubmed.ncbi.nlm.nih.gov/38414376/). *Int J Low Extrem Wounds*. [Review / Meta-Analysis]
Yoshioka N (2026). [PMID: 42028226](https://pubmed.ncbi.nlm.nih.gov/42028226/). *Front Neural Circuits*. [Basic Science / Preclinical]
Kender Z (2026). [PMID: 41991854](https://pubmed.ncbi.nlm.nih.gov/41991854/). *MMW Fortschr Med*. [Review / Meta-Analysis]
Borin GU (2026). [PMID: 42041800](https://pubmed.ncbi.nlm.nih.gov/42041800/). *Brain Sci*. [Diagnostic / Biomarker]
Dudic A (2026). [PMID: 40824224](https://pubmed.ncbi.nlm.nih.gov/40824224/). *J Pediatr Orthop*. [Epidemiology / Natural History]
Brødsgaard RB (2026). [PMID: 42177981](https://pubmed.ncbi.nlm.nih.gov/42177981/). *Diabetes Metab*. [Epidemiology / Natural History]
Rajput JPS (2026). [PMID: 41788111](https://pubmed.ncbi.nlm.nih.gov/41788111/). *Cureus*. [Review / Meta-Analysis]
Ziori M (2026). [PMID: 41713325](https://pubmed.ncbi.nlm.nih.gov/41713325/). *J Diabetes Complications*. [Epidemiology / Natural History]