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baroreflex failure - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

baroreflex failure

MONDO:0018617

Overview

Baroreflex failure is a rare disorder that causes fluctuations in blood pressure with episodes of severe hypertension (high blood pressure) and elevated heart rate in response to stress, exercise, and pain. Individuals may also have hypotension (low blood pressure) with normal or reduced heart rate during periods of rest. Symptoms of baroreflex failure may include headache, sweating, and a heart rate that does not respond to medications. The onset of baroreflex failure may be very abrupt or more gradual. In many cases, the cause of baroreflex failure is not known. However, baroreflex failure can result from surgery or radiation treatment for cancers of the neck, injury to the nerves involved in sensing blood pressure, or a degenerative neurologic disease. Treatment usually involves medications to control blood pressure and heart rate along with stress reduction techniques.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for baroreflex failure.

14 publications have been identified in PubMed for baroreflex failure. Research spans Review / Meta-Analysis (29%), Case Report / Case Series (29%), and Epidemiology / Natural History (21%).

Research Type	Count	% of Total
Research summaries	4	29%

Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 10:09 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:443084

GARD

Genetic and Rare Diseases Info Center

GARD:10664

Questions for Your Care Team

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baroreflex failure

Overview

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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