Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

postencephalitic Parkinson disease - Clinical Profile, Treatments & Trials | Kisho | Kisho

Rare Disease

postencephalitic Parkinson disease

MONDO:0001945

Also known as:postencephalitic Parkinsonism

Overview

A disease believed to be caused by a viral illness that triggers degeneration of the nerve cells in the substantia nigra. Overall, this degeneration leads to clinical parkinsonism.

Treatments1 FDA approved

ResearchLimited published research (5 articles)

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Resting tremor; and common findings: Fever, Slowness of movement (bradykinesia), Drowsiness, and Cogwheel rigidity and others. 41 total HPO annotations.

Organ System	Phenotype Count	Example Features
Brain and nerves	17	Resting tremor, Slowness of movement (bradykinesia), Cogwheel rigidity

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

1 FDA-approved treatment is available for postencephalitic Parkinson disease, including CARBIDOPA TABLETS (CARBIDOPA, approved 1977).

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Prognosis

Phenotype severity distribution: 1 very common feature, 10 common features.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for postencephalitic Parkinson disease.

7 publications have been identified in PubMed for postencephalitic Parkinson disease. Kisho has analyzed 5 by research type. Research spans Review / Meta-Analysis (40%), Basic Science / Preclinical (40%), and Case Report / Case Series (20%).

Recent Publications

Bonomo N (2026). [PMID: 42218820](https://pubmed.ncbi.nlm.nih.gov/42218820/). *J ECT*. [Case Report / Case Series]
Strobel S (2024). [PMID: 39329695](https://pubmed.ncbi.nlm.nih.gov/39329695/). *Cells*. [Basic Science / Preclinical]
Martini M (2024). [PMID: 38059885](https://pubmed.ncbi.nlm.nih.gov/38059885/). *Journal of the history of the neurosciences*. [Review / Meta-Analysis]
Brainin M (2024). [PMID: 38745394](https://pubmed.ncbi.nlm.nih.gov/38745394/). *European journal of neurology*. [Review / Meta-Analysis]
Tanaka H (2024). [PMID: 39036836](https://pubmed.ncbi.nlm.nih.gov/39036836/). *Neuropathology and applied neurobiology*. [Basic Science / Preclinical]

Data assembled from 5 of 12 sources · Last updated Sep 18, 2026, 10:40 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:97349

GARD

Genetic and Rare Diseases Info Center

GARD:19370

Questions for Your Care Team

→What are the benefits and potential side effects of CARBIDOPA for managing postencephalitic Parkinson disease?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Kisho

postencephalitic Parkinson disease

Overview

Clinical Presentation

Treatment

Approved Therapies

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Clinical Trials

postencephalitic Parkinson disease

Overview

Clinical Presentation

Treatment

Approved Therapies

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Clinical Trials