autosomal dominant non-syndromic intellectual disability - Symptoms, Causes & Research | Kisho | Kisho

autosomal dominant non-syndromic intellectual disability

Rare Disease

MONDO:0015802

Also known as:

autosomal dominant mental retardationautosomal dominant non-syndromic intellectual disabilityautosomal dominant non-syndromic mental retardation

Autosomal dominant form of non-syndromic intellectual disability.

Genes

Clinical Trials

1 active

Newborn Screening

–

Patient Groups

–

Patient-Friendly Information

Comprehensive, easy-to-understand information about this condition

How we create this content →

Last reviewed: Feb 2026

Evidence base: Early

Find Clinical TrialsTrials

Clinical Trials

Research studies investigating treatments and therapies for this condition.

Active Trials

Total Trials

Filter trials on ClinicalTrials.gov:

View Recruiting Trials View All Trials

Data from ClinicalTrials.gov Jan 6, 2026

Clinical Trials

Research studies investigating treatments and therapies for this condition.

Active Trials

Total Trials

Filter trials on ClinicalTrials.gov:

View Recruiting Trials View All Trials

Data from ClinicalTrials.gov Jan 6, 2026

Overview

Limited structured data is available for this condition. Information continues to be gathered as research progresses.(5 data sources · Data coverage: Limited)

Overview

Autosomal dominant non-syndromic intellectual disability is an extremely rare condition. Because few cases have been documented, detailed clinical information is limited.

Symptoms & Signs

The condition is characterized by an autosomal dominant inheritance pattern. However, specific associated genes and phenotypes have not been documented. There are currently no orphan drug designations under investigation for this condition.

Prognosis & Outlook

Patients and caregivers are encouraged to seek genetic counseling to better understand the implications of this inherited condition. Connecting with rare disease registries, such as Orphanet, may provide additional resources and support. Finding specialists experienced with intellectual disabilities can also be beneficial.

Quick Resources

Helpful links for rare disease information and support

GARD (Genetic and Rare Diseases Information Center)NORD (National Organization for Rare Disorders)Find a Genetic Counselor

General Questions to Consider

Questions that may be helpful when speaking with your healthcare team

•Are there specialists or centers of excellence with experience in this condition?
•Is there a patient registry I could participate in?
•Should my family members consider genetic testing?
•What clinical trials might be available for this condition?
•Are there patient advocacy groups I should connect with?

Clinical

Associated Genes

10 genes

DPP6 CIC CAMK2A TLK2 ZBTB18 TBL1XR1 NAA15 KMT5B AP2M1 TRIO

Gene data from HGNC • Click to view on NCBI Gene

Treatment

Clinical Trials

Research studies investigating treatments and therapies for this condition.

Active Trials

Total Trials

Filter trials on ClinicalTrials.gov:

View Recruiting Trials View All Trials

Data from ClinicalTrials.gov Jan 6, 2026

Support

External Resources

Orphanet

European rare disease database

Orphanet:178469

GARD

Genetic and Rare Diseases Info Center

GARD:12107

Know a Patient Advocacy Group for this condition?

Help patients and families find support by registering your organization or suggesting a group that serves this community.

Was this helpful?

AI-Generated Content: This summary was generated using AI. Always consult with qualified healthcare providers for medical guidance.

Need this data in your product?

Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.

Explore API Start Free

← Back to All Diseases

autosomal dominant non-syndromic intellectual disability

Patient-Friendly Information

Clinical Trials

Clinical Trials

Overview

Overview

Symptoms & Signs

Prognosis & Outlook

Quick Resources

General Questions to Consider

Clinical

Associated Genes

Treatment

Clinical Trials

Support

External Resources

Orphanet

GARD

Related Diseases

Know a Patient Advocacy Group for this condition?

Need this data in your product?