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A carcinoma that arises from glandular epithelial cells of the bile duct
Biomarker and diagnostic research for bile duct adenocarcinoma has been reported in the published literature.
6 clinical trials registered, 2 recruiting. Interventions under study include drug therapy, procedural interventions, biologic therapy, and other interventions. Pipeline includes 1 PHASE4, 3 PHASE2, 2 PHASE1. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT03257761](https://clinicaltrials.gov/study/NCT03257761) |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 3:01 PM UTC
Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer |
PHASE1 |
University of Southern California |
ACTIVE_NOT_RECRUITING |
[NCT04941287](https://clinicaltrials.gov/study/NCT04941287) | Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer | PHASE2 | National Cancer Institute (NCI) | ACTIVE_NOT_RECRUITING |
[NCT05285358](https://clinicaltrials.gov/study/NCT05285358) | Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases | PHASE1 | City of Hope Medical Center | RECRUITING |
[NCT07120295](https://clinicaltrials.gov/study/NCT07120295) | Study of Large Channel Digital Pancreaticobiliary Scope (DPS) With Compatible Accessories | PHASE4 | University of Colorado, Denver | RECRUITING |
[NCT06383533](https://clinicaltrials.gov/study/NCT06383533) | Disitamab Vedotin Plus Cadonilimab in Patients With HER2 Mutant Advanced or Metastatic Bile Duct Adenocarcinoma | PHASE2 | Zhejiang Cancer Hospital | UNKNOWN |
14 publications have been identified in PubMed for bile duct adenocarcinoma. Research spans Case Report / Case Series (36%), Clinical Trial Publication (29%), and Review / Meta-Analysis (14%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 5 | 36% |
Clinical study results | 4 | 29% |
Research summaries | 2 | 14% |
Disease patterns and progression | 2 | 14% |
Testing and diagnosis research | 1 | 7% |
Delis S (2026). [PMID: 41664944](https://pubmed.ncbi.nlm.nih.gov/41664944/). *Acta medica academica*. [Case Report / Case Series]
Madroñal Escribano PJ (2026). [PMID: 41672852](https://pubmed.ncbi.nlm.nih.gov/41672852/). *Transplantation proceedings*. [Review / Meta-Analysis]
Sonoda H (2026). [PMID: 41749936](https://pubmed.ncbi.nlm.nih.gov/41749936/). *Cancers*. [Case Report / Case Series]
Kaps L (2025). [PMID: 39905306](https://pubmed.ncbi.nlm.nih.gov/39905306/). *BMC gastroenterology*. [Clinical Trial Publication]
Choi N (2025). [PMID: 41230291](https://pubmed.ncbi.nlm.nih.gov/41230291/). *Cureus*. [Clinical Trial Publication]
Egawa N (2025). [PMID: 41458095](https://pubmed.ncbi.nlm.nih.gov/41458095/). *Surgical case reports*. [Case Report / Case Series]
Alshwayyat S (2025). [PMID: 40033199](https://pubmed.ncbi.nlm.nih.gov/40033199/). *International journal of emergency medicine*. [Case Report / Case Series]
Formanchuk TV (2025). [PMID: 41518165](https://pubmed.ncbi.nlm.nih.gov/41518165/). *Wiadomosci lekarskie (Warsaw, Poland : 1960)*. [Epidemiology / Natural History]
Wu J (2025). [PMID: 40667538](https://pubmed.ncbi.nlm.nih.gov/40667538/). *American journal of cancer research*. [Case Report / Case Series]
Ecker BL (2024). [PMID: 39259526](https://pubmed.ncbi.nlm.nih.gov/39259526/). *JAMA surgery*. [Diagnostic / Biomarker]
AI-curated news mentioning bile duct adenocarcinoma
Updated Feb 9, 2026
A new study explores a minimally invasive approach to address bile duct stricture following laparoscopic hepatectomy. This research could enhance surgical outcomes and recovery for patients experiencing this complication.