Bile Duct Adenocarcinoma — Clinical Trials

MONDO:00031935 active·3 recruitingLast updated: Mar 20, 2026, 9:50 AM

Trial Landscape

Bile Duct Adenocarcinoma has an emerging clinical trial program, driven by drug treatment and biological therapy.

Recruiting

Active Trials

By Approach

Drug Treatment4

Biological Therapy2

Medical Device1

Procedure1

1 additional trials involve behavioral, dietary, diagnostic, or observational approaches.

By Phase

Phase 1

Phase 2

Phase 4

Sponsor Types

Academic/Other4NIH1

Trial Locations

United States4 trials

China1 trial

Trials often recruit across multiple countries, so totals exceed the trial count.

5 Trials

Phase 2Recruiting

NCT06383533

Disitamab Vedotin Plus Cadonilimab in Patients With HER2 Mutant Advanced or Metastatic Bile Duct Adenocarcinoma

Sponsor:Zhejiang Cancer Hospital

ChinaStarted: May 2023Est. completion: Dec 2025Updated: Apr 2024

Last updated over 18 months ago

Phase 1Recruiting

NCT05285358

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

Sponsor:City of Hope Medical Center

United StatesStarted: Sep 2022Est. completion: Oct 2028Updated: Mar 2026

Phase 4Recruiting

NCT07120295

Study of Large Channel Digital Pancreaticobiliary Scope (DPS) With Compatible Accessories

Sponsor:University of Colorado, Denver

United StatesStarted: Aug 2025Est. completion: Dec 2028Updated: Sep 2025

Phase 2Active, Not Recruiting

NCT04941287

Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer

Sponsor:National Cancer Institute (NCI)

United StatesStarted: Dec 2021Est. completion: Apr 2026Updated: May 2025

Phase 1Active, Not Recruiting

NCT03257761

Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer

Sponsor:University of Southern California

United StatesStarted: Feb 2018Est. completion: Jul 2026Updated: Dec 2025

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Data sourced from ClinicalTrials.gov via Kisho's automated pipeline. Trials refreshed every 4 hours for monitored diseases.

Last sync: March 20, 2026 at 9:50 AM