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Back to Bone Marrow Failure Syndrome

Bone Marrow Failure Syndrome — NIH Grants & Funding

Active and recent NIH-funded research on Bone Marrow Failure Syndrome. Data from NIH RePORTER, last 36 months.

MONDO:0000159

NIH-funded research on Bone Marrow Failure Syndrome

active grants

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new in last 12 mo.

$47.3M in NIH funding over the last 36 months. Data from NIH RePORTER.

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Basic Science(11)

Basic ScienceZIACompleted

Immune Pathophysiology of Aplastic Anemia and Immunosuppressive Treatments

YOUNG, NEAL·NATIONAL HEART, LUNG, AND BLOOD INSTITUTE

$3,414,257 (FY2025)

Bone Marrow Failure Syndrome — NIH Grants & Funding

Basic Science(11)

Immune Pathophysiology of Aplastic Anemia and Immunosuppressive Treatments

FANCONI ANEMIA:GENOTYPE-PHENOTYPE CORRELATIONS

Red Cell Biology

Mechanisms and relevance of miRNA decay during hematopoietic development

Rewiring of RNA Polymerase II in a Novel Taspase1- Mediated Marrow Failure.

Elucidating function of disease-related SAMD9L mutations in hematopoiesis

Characterization of the Role of Nemo-like Kinase in Normal and Diamond Blackfan Anemia Models of Erythropoiesis.

Defining LncRNA Function in normal and Shwachman Diamond Syndrome Myelopoiesis

Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA)

Novel sources of endogenous DNA damage in hematopoietic stem progenitor cells

Translational(3)

Implications of PARP1 in myelodysplastic syndromes and targeted therapy

Molecular targeting of erythroid progenitor cells in normal and disordered human erythropoiesis

Unrelated Donor BMT vs. Immune Suppression for Newly Diagnosed Severe Aplastic Anemia in Children and Young Adults: BMT CTN Core Center Renewal for the Pediatric Blood and Marrow Transplant Consortium

Clinical(5)

Eltrombopag for the Treatment of Fanconi Anemia

Improving Inflammation Resolution to Mitigate Acquired Bone Marrow Failure

Stem cells for therapeutics discovery in genetic blood disorders

Enhancing Innate Immune Reconstitution Post Allogeneic HSCT.

Therapeutic Implications of Molecular Defects in Bone Marrow Failure

Epi / Nat. History(1)

Genetic Epidemiology of Telomere Maintenance and Cancer Etiology

Gene/Cell Therapy(2)

Gene Therapy for Inherited Blood Disorders

Generation of Hematopoietic Stem and Progenitor Cells from iPSCs