A usually aggressive malignant bone-forming mesenchymal neoplasm arising from the bone. It may arise de novo or from a pre-existing lesion of the bone. Pain and a palpable mass are the most frequent c...
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
The documentation surrounding bone osteosarcoma is limited due to its rarity and the complexity of its clinical features, which have not been systematically characterized. As the condition affects fewer than 10,000 individuals in the U.S., comprehensive clinical studies are challenging. Additionally, the genetic basis is still being explored, contributing to gaps in understanding and documentation.
To navigate your journey with bone osteosarcoma, consider seeking out a medical oncologist who specializes in sarcomas, as they will have the expertise necessary for managing this complex condition. Additionally, genetic counseling may be beneficial given the involvement of CHEK2 and RB1 genes; you can find a genetic counselor through the National Society of Genetic Counselors at findageneticcounselor.com. Participating in clinical trials may also provide access to cutting-edge treatments, so discussing eligibility with your healthcare team is essential.
Currently, there are 216 active clinical trials for bone osteosarcoma, reflecting ongoing research efforts to better understand and treat this condition. While there are no orphan drug designations, these trials may offer new insights into potential treatments. You can explore these opportunities further at ClinicalTrials.gov using the search term 'bone osteosarcoma'.
Actionable guidance for navigating care for bone osteosarcoma
To navigate your journey with bone osteosarcoma, consider seeking out a medical oncologist who specializes in sarcomas, as they will have the expertise necessary for managing this complex condition. Additionally, genetic counseling may be beneficial given the involvement of CHEK2 and RB1 genes; you can find a genetic counselor through the National Society of Genetic Counselors at findageneticcounselor.com. Participating in clinical trials may also provide access to cutting-edge treatments, so discussing eligibility with your healthcare team is essential.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Organizations with approved therapies for this disease
No approved therapies yet
Research is ongoing — 1 company has orphan drug designations for this disease
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.