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A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement.
Biomarker and diagnostic research for carcinoid tumor has been reported in the published literature.
32 clinical trials registered, 5 recruiting. Interventions under study include drug therapy, other interventions, procedural interventions, and medical devices. Pipeline includes 4 PHASE3, 10 PHASE2, 3 PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT04735198](https://clinicaltrials.gov/study/NCT04735198) |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 1:00 AM UTC
Prophylactic Cholecystectomy in Midgut NETs Patients Who Require Primary Tumor Surgery. |
NA |
Hospital Universitari de Bellvitge |
RECRUITING |
[NCT04907643](https://clinicaltrials.gov/study/NCT04907643) | Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes | NA | Cedars-Sinai Medical Center | RECRUITING |
[NCT05263050](https://clinicaltrials.gov/study/NCT05263050) | Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors | PHASE2 | Fox Chase Cancer Center | RECRUITING |
[NCT05969860](https://clinicaltrials.gov/study/NCT05969860) | At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer | PHASE2 | Mayo Clinic | RECRUITING |
[NCT00646022](https://clinicaltrials.gov/study/NCT00646022) | Natural History of Familial Carcinoid Tumor | — | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | RECRUITING |
287 publications have been identified in PubMed for carcinoid tumor. Kisho has analyzed 194 by research type. Research spans Case Report / Case Series (49%), Review / Meta-Analysis (13%), and Epidemiology / Natural History (11%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 96 | 49% |
Research summaries | 25 | 13% |
Disease patterns and progression | 21 | 11% |
Testing and diagnosis research | 19 | 10% |
Laboratory research | 17 | 9% |
Clinical study results | 12 | 6% |
Other research | 2 | 1% |
New treatment approaches | 2 | 1% |
Bhati G (2026). [PMID: 42098431](https://pubmed.ncbi.nlm.nih.gov/42098431/). *Discov Oncol*. [Case Report / Case Series]
Trecourt A (2026). [PMID: 41255082](https://pubmed.ncbi.nlm.nih.gov/41255082/). *Am J Surg Pathol*. [Basic Science / Preclinical]
Orlando G (2026). [PMID: 42165962](https://pubmed.ncbi.nlm.nih.gov/42165962/). *Endocr Pathol*. [Diagnostic / Biomarker]
Chauhan A (2026). [PMID: 41704395](https://pubmed.ncbi.nlm.nih.gov/41704395/). *Case Rep Endocrinol*. [Case Report / Case Series]
Mohamed Choukri M (2026). [PMID: 42181827](https://pubmed.ncbi.nlm.nih.gov/42181827/). *Open Respir Arch*. [Case Report / Case Series]
Kifjak D (2026). [PMID: 41216858](https://pubmed.ncbi.nlm.nih.gov/41216858/). *Curr Opin Oncol*. [Review / Meta-Analysis]
Bertolaccini L (2026). [PMID: 40560517](https://pubmed.ncbi.nlm.nih.gov/40560517/). *Updates Surg*. [Epidemiology / Natural History]
Jadoul A (2026). [PMID: 41247249](https://pubmed.ncbi.nlm.nih.gov/41247249/). *Clin Nucl Med*. [Case Report / Case Series]
Al Tabaa O (2026). [PMID: 41640080](https://pubmed.ncbi.nlm.nih.gov/41640080/). *Am J Case Rep*. [Case Report / Case Series]
Çam I (2026). [PMID: 41486255](https://pubmed.ncbi.nlm.nih.gov/41486255/). *J Cardiothorac Surg*. [Case Report / Case Series]
AI-curated news mentioning carcinoid tumor
Updated May 7, 2026
A case report details an unusual presentation of a jejunal carcinoid tumor leading to intussusception and vertebral metastasis. This finding may provide insights into the complexities of carcinoid tumors and their metastatic behavior.