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central nervous system germ cell tumor - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

central nervous system germ cell tumor

MONDO:0003000

Also known as:CNS germ cell neoplasmCNS germ cell tumorCNS germ cell tumour

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Overview

A unique group of rare tumors of the central nervous system that affect mainly children and adolescents. Their morphologic and biologic profile corresponds to that of homologous germ cell tumors that arise in the gonads and in other extragonadal sites. Representative examples include: germinoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma.

Clinical Trials2 registered

Diagnosis

Biomarker and diagnostic research for central nervous system germ cell tumor has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

2 clinical trials registered. Interventions under study include other interventions and procedural interventions. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.

168 publications have been identified in PubMed for central nervous system germ cell tumor. Research spans Review / Meta-Analysis (31%), Basic Science / Preclinical (29%), and Diagnostic / Biomarker (10%).

Research Type	Count	% of Total
Research summaries	52

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 9:00 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 2 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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central nervous system germ cell tumor

Overview

Diagnosis

Research Landscape

Medical References

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Questions for Your Care Team

Questions for Your Care Team

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