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Circumscribed collections of suppurative material occurring in the spinal or intracranial epidural space. The majority of epidural abscesses occur in the spinal canal and are associated with osteomyelitis of a vertebral body; analgesia, epidural; and other conditions. Clinical manifestations include local and radicular pain, weakness, sensory loss, urinary incontinence, and fecal incontinence. Cranial epidural abscesses are usually associated with osteomyelitis of a cranial bone, sinusitis, or otitis media. (From Adams et al., Principles of Neurology, 6th ed, p710 and pp1240-1; J Neurol Neurosurg Psychiatry 1998 Aug;65(2):209-12)
Biomarker and diagnostic research for epidural abscess has been reported in the published literature.
2 clinical trials registered, 1 recruiting. Interventions under study include other interventions. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.
220 publications have been identified in PubMed for epidural abscess. Kisho has analyzed 121 by research type. Research spans Case Report / Case Series (48%), Review / Meta-Analysis (21%), and Epidemiology / Natural History (17%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 58 |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 6:00 AM UTC
Research summaries | 26 | 21% |
Disease patterns and progression | 21 | 17% |
Testing and diagnosis research | 8 | 7% |
Clinical study results | 4 | 3% |
Other research | 2 | 2% |
Laboratory research | 2 | 2% |
Budiman L (2026). [PMID: 41479378](https://pubmed.ncbi.nlm.nih.gov/41479378/). *Emerg Med Australas*. [Review / Meta-Analysis]
Yang IF (2026). [PMID: 42163441](https://pubmed.ncbi.nlm.nih.gov/42163441/). *Am J Case Rep*. [Case Report / Case Series]
Windsor TA (2026). [PMID: 41895885](https://pubmed.ncbi.nlm.nih.gov/41895885/). *Emerg Med Clin North Am*. [Review / Meta-Analysis]
Gausper A (2026). [PMID: 42176015](https://pubmed.ncbi.nlm.nih.gov/42176015/). *Eur Spine J*. [Epidemiology / Natural History]
Chen Z (2026). [PMID: 41795116](https://pubmed.ncbi.nlm.nih.gov/41795116/). *J Orthop Surg Res*. [Basic Science / Preclinical]
Şahin A (2026). [PMID: 41214469](https://pubmed.ncbi.nlm.nih.gov/41214469/). *Pediatr Infect Dis J*. [Diagnostic / Biomarker]
Regev A (2026). [PMID: 41593845](https://pubmed.ncbi.nlm.nih.gov/41593845/). *Pediatr Infect Dis J*. [Review / Meta-Analysis]
Abraham MK (2026). [PMID: 41260852](https://pubmed.ncbi.nlm.nih.gov/41260852/). *Emerg Med Clin North Am*. [Review / Meta-Analysis]
Tande AJ (2026). [PMID: 42019020](https://pubmed.ncbi.nlm.nih.gov/42019020/). *N Engl J Med*. [Review / Meta-Analysis]
Das JM (2026). [PMID: 29630279](https://pubmed.ncbi.nlm.nih.gov/29630279/). *Unknown Journal*. [Case Report / Case Series]
AI-curated news mentioning epidural abscess
Updated May 14, 2026
A case report details a rare instance of clostridial spondylodiscitis and epidural abscess linked to spinal lymphoma in the thoracic spine. This complex case highlights the challenges in diagnosing and managing overlapping rare conditions.
A study published in PubMed reveals that severe initial neurological deficits in patients with isolated Staphylococcus aureus spinal epidural abscesses do not lead to worse outcomes compared to those with spondylodiscitis. This finding may influence treatment approaches and patient management strategies.