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A well-circumscribed mass composed of tuberculous granulation tissue that may occur in the cerebral hemispheres, cerebellum, brain stem, or perimeningeal spaces. Multiple lesions are quite common. Management of intracranial manifestations vary with lesion site. Intracranial tuberculomas may be associated with seizures, focal neurologic deficits, and intracranial hypertension. Spinal cord tuberculomas may be associated with localized or radicular pain, weakness, sensory loss, and incontinence. Tuberculomas may arise as opportunistic infections, but also occur in immunocompetent individuals.
Biomarker and diagnostic research for central nervous system tuberculosis has been reported in the published literature.
No clinical trials have been registered for central nervous system tuberculosis.
162 publications have been identified in PubMed for central nervous system tuberculosis. Kisho has analyzed 117 by research type. Research spans Case Report / Case Series (46%), Review / Meta-Analysis (17%), and Epidemiology / Natural History (15%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 54 | 46% |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 4:06 PM UTC
European rare disease database
Research summaries |
20 |
17% |
Disease patterns and progression | 17 | 15% |
Laboratory research | 9 | 8% |
Testing and diagnosis research | 8 | 7% |
New treatment approaches | 4 | 3% |
Clinical study results | 3 | 3% |
Other research | 2 | 2% |
Garg RK (2026). [PMID: 41123477](https://pubmed.ncbi.nlm.nih.gov/41123477/). *Expert Rev Anti Infect Ther*. [Review / Meta-Analysis]
Barone C (2026). [PMID: 42081272](https://pubmed.ncbi.nlm.nih.gov/42081272/). *Pediatr Infect Dis J*. [Case Report / Case Series]
Endara-Mina J (2026). [PMID: 41810237](https://pubmed.ncbi.nlm.nih.gov/41810237/). *Front Med (Lausanne)*. [Case Report / Case Series]
Parchinski K (2026). [PMID: 41438010](https://pubmed.ncbi.nlm.nih.gov/41438010/). *J Clin Tuberc Other Mycobact Dis*. [Epidemiology / Natural History]
Kumar D SS (2026). [PMID: 41856917](https://pubmed.ncbi.nlm.nih.gov/41856917/). *Clin Infect Dis*. [Epidemiology / Natural History]
Carter EC (2026). [PMID: 42242389](https://pubmed.ncbi.nlm.nih.gov/42242389/). *J Infect*. [Epidemiology / Natural History]
Takahashi-Iwata I (2026). [PMID: 42156029](https://pubmed.ncbi.nlm.nih.gov/42156029/). *Brain Nerve*. [Review / Meta-Analysis]
Zhu H (2026). [PMID: 41680651](https://pubmed.ncbi.nlm.nih.gov/41680651/). *BMC Infect Dis*. [Basic Science / Preclinical]
Gupta NK (2026). [PMID: 41575229](https://pubmed.ncbi.nlm.nih.gov/41575229/). *Ann Afr Med*. [Case Report / Case Series]
Dorukoğlu M (2026). [PMID: 41714987](https://pubmed.ncbi.nlm.nih.gov/41714987/). *BMC Neurol*. [Epidemiology / Natural History]
AI-curated news mentioning central nervous system tuberculosis
Updated May 9, 2026
A recent study published in PubMed explores the dissemination patterns of central nervous system Burkitt lymphoma, specifically from the fornix to the ventricles. This research may provide insights into the disease's progression and potential treatment strategies.