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central nervous system germinoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

central nervous system germinoma

MONDO:0002999

Also known as:central nervous system germinoma (disease)germinoma of CNSgerminoma of central nervous system

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Overview

A malignant germ cell tumor arising from the central nervous system. It is composed of uniform cells resembling primitive germ cells. These cells have large, vesicular nuclei, prominent nucleoli and a clear, glycogen-rich cytoplasm. Additional features are lymphoid or lymphoplasmacytic infiltrates and, less frequently, scattered syncytiotrophoblastic giant cells. (Adapted from WHO)

Clinical Trials5 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for central nervous system germinoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

5 clinical trials registered, 3 recruiting. Interventions under study include procedural interventions, other interventions, and drug therapy. Pipeline includes 1 PHASE3, 1 PHASE2. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT04648462](https://clinicaltrials.gov/study/NCT04648462)

Data assembled from 3 of 12 sources · Last updated Oct 4, 2026, 12:12 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 5 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Research summaries	7	24%
Patient case studies	7	24%
Disease patterns and progression	6	21%
Testing and diagnosis research	4	14%
Clinical study results	3	10%
Laboratory research	2	7%

central nervous system germinoma

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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