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Chancroid is a bacterial infection that is spread through sexual contact. It is caused by a type of bacteria called Haemophilus ducreyi. Chancroid is characterized by a small bump on the genital which becomes a painful ulcer. Men may have just one ulcer, but women often develop four or more.About half of the people who are infected with a chancroid will develop enlarged inguinal lymph nodes, the nodes located in the fold between the leg and the lower abdomen. In some cases, the nodes will break through the skin and cause draining abscesses. The swollen lymph nodes and abscesses are often called buboes. Chancroid infections can be treated with antibiotics, including azithromycin, ceftriaxone, ciprofloxacin, and erythromycin. Large lymph node swellings need to be drained, either with a needle or local surgery.
No clinical trials have been registered for chancroid.
32 publications have been identified in PubMed for chancroid. Research spans Epidemiology / Natural History (31%), Review / Meta-Analysis (28%), and Basic Science / Preclinical (22%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 10 | 31% |
Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 6:52 PM UTC
Genetic and Rare Diseases Info Center
9 |
28% |
Laboratory research | 7 | 22% |
Patient case studies | 5 | 16% |
Clinical study results | 1 | 3% |
Lewis DA (2026). [PMID: 41046959](https://pubmed.ncbi.nlm.nih.gov/41046959/). *Clinics in dermatology*. [Review / Meta-Analysis]
Matoga MM (2026). [PMID: 40096547](https://pubmed.ncbi.nlm.nih.gov/40096547/). *Clinical infectious diseases : an official publication of the Infectious Diseases Society of America*. [Clinical Trial Publication]
Matoga MM (2026). [PMID: 41646416](https://pubmed.ncbi.nlm.nih.gov/41646416/). *Research square*. [Epidemiology / Natural History]
Damián-García R (2026). [PMID: 41637832](https://pubmed.ncbi.nlm.nih.gov/41637832/). *Semergen*. [Basic Science / Preclinical]
Majed L (2026). [PMID: 41694867](https://pubmed.ncbi.nlm.nih.gov/41694867/). *Cureus*. [Case Report / Case Series]
Ndzomo P (2026). [PMID: 41318902](https://pubmed.ncbi.nlm.nih.gov/41318902/). *Current opinion in infectious diseases*. [Review / Meta-Analysis]
Choi JB (2026). [PMID: 41492832](https://pubmed.ncbi.nlm.nih.gov/41492832/). *Journal of Korean medical science*. [Review / Meta-Analysis]
Agbanyo A (2026). [PMID: 41911295](https://pubmed.ncbi.nlm.nih.gov/41911295/). *PLoS Negl Trop Dis*. [Epidemiology / Natural History]
Golparian D (2026). [PMID: 42148639](https://pubmed.ncbi.nlm.nih.gov/42148639/). *Microbiol Resour Announc*. [Basic Science / Preclinical]
Kamara IF (2026). [PMID: 42031294](https://pubmed.ncbi.nlm.nih.gov/42031294/). *Int J Infect Dis*. [Epidemiology / Natural History]