Cogan-Reese syndrome is a specific form of iridocorneal endothelial (ICE) syndrome. In people with this condition, changes can happen in the iris and the clear front part of the eye called the cornea. The iris may show areas of thinning and small, raised, pigmented growths. These changes are a hallmark of the syndrome and can vary from person to person. In addition to these iris changes, many people with this condition can develop secondary glaucoma—a rise in pressure inside the eye that can affect vision. The information provided focuses on the key features of the condition, highlighting its unique effects on the iris and cornea.

People with Cogan-Reese syndrome may experience thinning (atrophy) of the iris, the presence of small pigmented nodules on the iris, and abnormal changes in the cornea. A common symptom is the development of secondary glaucoma, which involves increased eye pressure.

Information about causes is currently limited for this condition.