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Congenital megacalycosis is a rare renal malformation, characterized by non-obstructive dilation of the renal calyces as well as an increased calyceal number (12-20), with a normal renal pelvis, ureter, and bladder. It may be unilateral or bilateral and is usually asymptomatic unless complicated by nephrolithiasis and urinary tract infection.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for congenital megacalycosis.
1 publication has been identified in PubMed for congenital megacalycosis. Research spans Review / Meta-Analysis (100%).
Jhala T (2025). [PMID: 40505808](https://pubmed.ncbi.nlm.nih.gov/40505808/). *J Pediatr Surg*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:45 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center