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Cor triatriatum sinister (CTS) results when the left atrium is divided into two compartments by a membrane. The membrane can vary in size and shape and may have one or more openings. Severe cases of cor triatriatum sinister usually present in infancy and are often associated with other heart defects. In less severe cases, the diagnosis may not be made until later in life. The specific symptoms depend on the degree to which the membrane obstructs the flow of blood and whether or not there are additional heart defects. Symptoms may range from mild shortness of breath during exercise to signs of heart failure and lung congestion. Some people with CTS may not have symptoms. Treatment varies according to the severity of the symptoms. For symptomatic patients, surgery is generally consideredthe definitive course of therapy.
No clinical trials have been registered for cor triatriatum sinister.
52 publications have been identified in PubMed for cor triatriatum sinister. Research spans Case Report / Case Series (85%), Review / Meta-Analysis (6%), and Other (4%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 44 | 85% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 11:21 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
3 |
6% |
Other research | 2 | 4% |
Disease patterns and progression | 2 | 4% |
New treatment approaches | 1 | 2% |
Chen Y (2026). [PMID: 42149936](https://pubmed.ncbi.nlm.nih.gov/42149936/). *Eur Heart J*. [Case Report / Case Series]
Mizuno Y (2026). [PMID: 42028073](https://pubmed.ncbi.nlm.nih.gov/42028073/). *HeartRhythm Case Rep*. [Case Report / Case Series]
İştar H (2026). [PMID: 41564914](https://pubmed.ncbi.nlm.nih.gov/41564914/). *Ann Thorac Surg*. [Other]
Yan Y (2026). [PMID: 42015163](https://pubmed.ncbi.nlm.nih.gov/42015163/). *J Cardiothorac Surg*. [Case Report / Case Series]
Masuda H (2026). [PMID: 41732474](https://pubmed.ncbi.nlm.nih.gov/41732474/). *HeartRhythm Case Rep*. [Case Report / Case Series]
Intravaia RCM (2026). [PMID: 42200269](https://pubmed.ncbi.nlm.nih.gov/42200269/). *G Ital Cardiol (Rome)*. [Case Report / Case Series]
Kardos M (2026). [PMID: 41794615](https://pubmed.ncbi.nlm.nih.gov/41794615/). *An Pediatr (Engl Ed)*. [Case Report / Case Series]
Papakonstantinou PE (2026). [PMID: 42038667](https://pubmed.ncbi.nlm.nih.gov/42038667/). *Heart Rhythm O2*. [Other]
Witte LS (2026). [PMID: 41993939](https://pubmed.ncbi.nlm.nih.gov/41993939/). *Eur Heart J Case Rep*. [Case Report / Case Series]
Apostolos A (2026). [PMID: 41957543](https://pubmed.ncbi.nlm.nih.gov/41957543/). *J Clin Ultrasound*. [Case Report / Case Series]
AI-curated news mentioning cor triatriatum sinister
Updated Sep 16, 2026
A recent study explores the use of transcatheter edge-to-edge mitral valve repair for patients with severe degenerative mitral regurgitation and coexisting cor triatriatum sinistrum. This research highlights potential advancements in minimally invasive cardiac interventions.
A recent publication highlights a rare congenital abnormality, cor triatriatum sinister, presenting in adults with anomalous coronary venous drainage into the left atrium. This discovery adds to the understanding of congenital heart defects and their adult manifestations.
A young woman was incidentally diagnosed with cor triatriatum sinister, a rare cardiac anomaly characterized by an abnormal partitioning of the left atrium. This case highlights the importance of thorough cardiac evaluation in young patients.