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Abnormal protrusion of one or more of the leaflets of tricuspid valve into the right atrium during systole. This allows the backflow of blood into right atrium leading to tricuspid valve insufficiency; systolic murmurs. Its most common cause is not primary valve abnormality but rather the dilation of the right ventricle and the tricuspid annulus.
Biomarker and diagnostic research for tricuspid valve prolapse has been reported in the published literature.
No clinical trials have been registered for tricuspid valve prolapse.
50 publications have been identified in PubMed for tricuspid valve prolapse. Research spans Epidemiology / Natural History (30%), Case Report / Case Series (28%), and Review / Meta-Analysis (18%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 15 | 30% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:40 AM UTC
European rare disease database
Patient case studies
14 |
28% |
Research summaries | 9 | 18% |
Clinical study results | 6 | 12% |
Testing and diagnosis research | 3 | 6% |
Other research | 2 | 4% |
Laboratory research | 1 | 2% |
Raslan M (2026). [PMID: 41918666](https://pubmed.ncbi.nlm.nih.gov/41918666/). *Cureus*. [Case Report / Case Series]
Sheikh M (2026). [PMID: 42220866](https://pubmed.ncbi.nlm.nih.gov/42220866/). *Cureus*. [Case Report / Case Series]
Haghani Nejad H (2026). [PMID: 41953898](https://pubmed.ncbi.nlm.nih.gov/41953898/). *Health Sci Rep*. [Epidemiology / Natural History]
Stark VC (2026). [PMID: 42073082](https://pubmed.ncbi.nlm.nih.gov/42073082/). *Children (Basel)*. [Epidemiology / Natural History]
Sjöbring O (2026). [PMID: 41844437](https://pubmed.ncbi.nlm.nih.gov/41844437/). *J Vet Cardiol*. [Epidemiology / Natural History]
Fusco F (2026). [PMID: 42281483](https://pubmed.ncbi.nlm.nih.gov/42281483/). *Echocardiography*. [Basic Science / Preclinical]
Berg-Hansen CE (2026). [PMID: 41679396](https://pubmed.ncbi.nlm.nih.gov/41679396/). *J Am Soc Echocardiogr*. [Epidemiology / Natural History]
Abdul Nabi H (2026). [PMID: 42229999](https://pubmed.ncbi.nlm.nih.gov/42229999/). *Open Heart*. [Epidemiology / Natural History]
Wijngaarden ALV (2026). [PMID: 41892694](https://pubmed.ncbi.nlm.nih.gov/41892694/). *Journal of cardiovascular development and disease*. [Epidemiology / Natural History]
Yurdakul Ertürk E (2026). [PMID: 41961718](https://pubmed.ncbi.nlm.nih.gov/41961718/). *Medicine (Baltimore)*. [Epidemiology / Natural History]
AI-curated news mentioning tricuspid valve prolapse
Updated Jul 28, 2026
A recent study highlights the severe consequences of pregnancy complicated by tricuspid valve nonbacterial thrombotic endocarditis. This research underscores the need for increased awareness and management strategies for this rare condition during pregnancy.