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Straddling or overriding tricuspid valve is a rare, congenital, tricuspid valve malformation characterized by the tricuspid valve that overrides the ventricular septum and communicates with both ventricles, as part of the tension apparatus of the valve crosses the ventricular septal defect and is attached in the left ventricle. The anomaly occurs with other congenital heart defects (transposition of great vessels, left ventricle outflow tract obstruction, double outlet right ventricle, hypoplastic right ventricle), which determine the main clinical manifestation.
Biomarker and diagnostic research for straddling or overriding tricuspid valve has been reported in the published literature.
No clinical trials have been registered for straddling or overriding tricuspid valve.
188 publications have been identified in PubMed for straddling or overriding tricuspid valve. Research spans Basic Science / Preclinical (25%), Case Report / Case Series (22%), and Clinical Trial Publication (18%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 39 | 25% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:45 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Patient case studies
35 |
22% |
Clinical study results | 29 | 18% |
Research summaries | 23 | 15% |
Disease patterns and progression | 20 | 13% |
Testing and diagnosis research | 8 | 5% |
New treatment approaches | 2 | 1% |
Other research | 1 | 1% |
Kuijjer M (2026). [PMID: 41867852](https://pubmed.ncbi.nlm.nih.gov/41867852/). *bioRxiv*. [Epidemiology / Natural History]
Atici SG (2026). [PMID: 42150153](https://pubmed.ncbi.nlm.nih.gov/42150153/). *Med Anthropol Q*. [Gene Therapy / Novel Therapeutics]
Talukdar D (2026). [PMID: 42068276](https://pubmed.ncbi.nlm.nih.gov/42068276/). *ACS Appl Mater Interfaces*. [Basic Science / Preclinical]
Horie S (2026). [PMID: 41501943](https://pubmed.ncbi.nlm.nih.gov/41501943/). *Gen Thorac Cardiovasc Surg Cases*. [Case Report / Case Series]
Krebushevski K (2026). [PMID: 40997249](https://pubmed.ncbi.nlm.nih.gov/40997249/). *World J Pediatr Congenit Heart Surg*. [Case Report / Case Series]
Ward C (2026). [PMID: 41885106](https://pubmed.ncbi.nlm.nih.gov/41885106/). *Aust N Z J Obstet Gynaecol*. [Review / Meta-Analysis]
Hung YP (2026). [PMID: 41293870](https://pubmed.ncbi.nlm.nih.gov/41293870/). *Histopathology*. [Clinical Trial Publication]
Wu B (2026). [PMID: 41610700](https://pubmed.ncbi.nlm.nih.gov/41610700/). *Eur J Radiol*. [Diagnostic / Biomarker]
Byer SH (2026). [PMID: 41608071](https://pubmed.ncbi.nlm.nih.gov/41608071/). *Eur Heart J Case Rep*. [Case Report / Case Series]
Chanouha N (2026). [PMID: 41492223](https://pubmed.ncbi.nlm.nih.gov/41492223/). *J Genet Couns*. [Basic Science / Preclinical]