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Ebstein's malformation is a rare congenital cardiac anomaly characterized by rotational displacement of the septal and inferior leaflets of the tricuspid valve such that they are hinged within the right ventricle, rather than as expected at the atrioventricular junction.
Features include: Atrial standstill, Atrial fibrillation, Complete right bundle branch block, and Ventricular preexcitation and 3 more.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 6 | Atrial standstill, Atrial fibrillation, Complete right bundle branch block |
Biomarker and diagnostic research for Ebstein anomaly has been reported in the published literature.
Estimated prevalence: 1-9 in 100,000 (Uncommon).
1 clinical trial registered. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.
208 publications have been identified in PubMed for Ebstein anomaly. Research spans Case Report / Case Series (44%), Review / Meta-Analysis (17%), and Epidemiology / Natural History (13%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 91 | 44% |
Data assembled from 6 of 12 sources · Last updated Sep 19, 2026, 3:29 AM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Ebstein anomaly
Research summaries |
35 |
17% |
Disease patterns and progression | 28 | 13% |
Clinical study results | 19 | 9% |
Other research | 14 | 7% |
Testing and diagnosis research | 11 | 5% |
Laboratory research | 6 | 3% |
New treatment approaches | 4 | 2% |
Deng MX (2026). [PMID: 41567992](https://pubmed.ncbi.nlm.nih.gov/41567992/). *Int J Cardiol Congenit Heart Dis*. [Review / Meta-Analysis]
Ing RJ (2026). [PMID: 41006072](https://pubmed.ncbi.nlm.nih.gov/41006072/). *J Cardiothorac Vasc Anesth*. [Other]
Unknown (2026). [PMID: 41703932](https://pubmed.ncbi.nlm.nih.gov/41703932/). *Eur J Cardiothorac Surg*. [Other]
Nguyen HC (2026). [PMID: 41845492](https://pubmed.ncbi.nlm.nih.gov/41845492/). *J Cardiothorac Surg*. [Case Report / Case Series]
Neumann S (2026). [PMID: 41779126](https://pubmed.ncbi.nlm.nih.gov/41779126/). *Clin Res Cardiol*. [Epidemiology / Natural History]
Schouw ME (2026). [PMID: 41772445](https://pubmed.ncbi.nlm.nih.gov/41772445/). *BMC Cardiovasc Disord*. [Case Report / Case Series]
Klaučo F (2026). [PMID: 42073991](https://pubmed.ncbi.nlm.nih.gov/42073991/). *Int J Mol Sci*. [Basic Science / Preclinical]
Șuteu CC (2026). [PMID: 42073478](https://pubmed.ncbi.nlm.nih.gov/42073478/). *Life (Basel)*. [Diagnostic / Biomarker]
Liu X (2026). [PMID: 41764505](https://pubmed.ncbi.nlm.nih.gov/41764505/). *J Cardiothorac Surg*. [Case Report / Case Series]
Chen Q (2026). [PMID: 41792936](https://pubmed.ncbi.nlm.nih.gov/41792936/). *Int J Gynaecol Obstet*. [Diagnostic / Biomarker]
AI-curated news mentioning Ebstein anomaly
Updated May 14, 2026
A case report details late-onset third-degree atrioventricular block in an adult with surgically corrected Ebstein anomaly. This finding contributes to the understanding of potential long-term cardiac complications in patients with this congenital heart defect.