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core binding factor acute myeloid leukemia - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

core binding factor acute myeloid leukemia

MONDO:0850269

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Overview

An acute myeloid leukemia that is characterized by the presence of t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22). These cytogenetic abnormalities result in disruption of the transcription factor CBF, which is a regulator of normal hematopoiesis.

Clinical Trials3 registered

Diagnosis

Biomarker and diagnostic research for core binding factor acute myeloid leukemia has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

3 clinical trials registered. Interventions under study include drug therapy and procedural interventions. Pipeline includes 2 PHASE2. Research is primarily sponsored by academic and government institutions.

34 publications have been identified in PubMed for core binding factor acute myeloid leukemia. Research spans Clinical Trial Publication (26%), Basic Science / Preclinical (18%), and Other (15%).

Research Type	Count	% of Total
Clinical study results	9

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:44 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 3 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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core binding factor acute myeloid leukemia

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications