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This syndrome is characterized by progressive sensorineural deafness, alopecia and hypogonadism with LH and GH deficiencies. It has been described in three brothers. It resembles Bjrnstad's syndrome that combines irregular pili torti and deafness. It is probably inherited as and autosomal recessive disorder.
No clinical trials have been registered for Crandall syndrome.
112 publications have been identified in PubMed for Crandall syndrome. Kisho has analyzed 57 by research type. Research spans Review / Meta-Analysis (63%), Basic Science / Preclinical (21%), and Case Report / Case Series (7%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 36 | 63% |
Laboratory research | 12 |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 3:02 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Crandall syndrome
Patient case studies | 4 | 7% |
Disease patterns and progression | 3 | 5% |
Clinical study results | 2 | 4% |
D'Onofrio G (2026). [PMID: 41670966](https://pubmed.ncbi.nlm.nih.gov/41670966/). *JAMA*. [Clinical Trial Publication]
Garduno AC (2026). [PMID: 42116597](https://pubmed.ncbi.nlm.nih.gov/42116597/). *J Gerontol A Biol Sci Med Sci*. [Epidemiology / Natural History]
Pignataro G (2025). [PMID: 41010942](https://pubmed.ncbi.nlm.nih.gov/41010942/). *Medicina (Kaunas)*. [Review / Meta-Analysis]
Lee KH (2025). [PMID: 38826421](https://pubmed.ncbi.nlm.nih.gov/38826421/). *bioRxiv*. [Basic Science / Preclinical]
Patel R (2025). [PMID: 40204117](https://pubmed.ncbi.nlm.nih.gov/40204117/). *J Neuroradiol*. [Basic Science / Preclinical]
Karuntu JS (2025). [PMID: 39733931](https://pubmed.ncbi.nlm.nih.gov/39733931/). *Prog Retin Eye Res*. [Review / Meta-Analysis]
Pena C (2025). [PMID: 40146047](https://pubmed.ncbi.nlm.nih.gov/40146047/). *Minerva Med*. [Review / Meta-Analysis]
Walther LE (2025). [PMID: 40192781](https://pubmed.ncbi.nlm.nih.gov/40192781/). *HNO*. [Review / Meta-Analysis]
Kaul A (2025). [PMID: 40915300](https://pubmed.ncbi.nlm.nih.gov/40915300/). *Lancet Rheumatol*. [Review / Meta-Analysis]
Agrawal R (2025). [PMID: 40200630](https://pubmed.ncbi.nlm.nih.gov/40200630/). *J Assoc Physicians India*. [Review / Meta-Analysis]