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NIH Grants & Funding for Cystic Fibrosis | Kisho | Kisho

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Cystic Fibrosis — NIH Grants & Funding

Active and recent NIH-funded research on Cystic Fibrosis. Data from NIH RePORTER, last 36 months.

MONDO:0009061

NIH-funded research on Cystic Fibrosis

active grants

institutions

162

researchers

new in last 12 mo.

$154.5M in NIH funding over the last 36 months. Data from NIH RePORTER.

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Basic Science(56)

Basic ScienceP30Active

Center for Cystic Fibrosis Translational Research in the Post-CFTR modulator Era

Goss, Christopher et al.·SEATTLE CHILDREN'S HOSPITAL·SEATTLE, WA

$1,313,622 (FY2025)

Cystic Fibrosis — NIH Grants & Funding

Basic Science(56)

Center for Cystic Fibrosis Translational Research in the Post-CFTR modulator Era

UNC Cystic Fibrosis Research and Translation Core Center

Personalized Cystic Fibrosis Therapy and Research Center

Precision Medicine Center for Cystic Fibrosis

The Role of Neutrophils in Cystic Fibrosis Pathogenesis

Engineering Novel Precision Genome Editing Tools

Discovery of novel lead-target pairs and identification of all-oral bactericidal drug regimens for Mycobacterium abscessus lung disease

Deciphering the role of the Cystic Fibrosis Transmembrane Receptor (CFTR) in dietary fatty acid transport in the small intestine

Investigating pulmonary ionocyte function and development using iPSCs

Pathogenic monocyte response to chronic lung inflammation in cystic fibrosis

Translational(19)

Pulmonary and pancreatic response to cystic fibrosis modulator therapy in young children

Rational optimization of combinatorial therapies for the treatment of rare cystic fibrosis variants

Development of novel approaches for gene editing therapies of cystic fibrosis

The role of anaerobic microbiota in cystic fibrosis airway disease trajectory

Optimizing ELD607 for Delivery by Inhalation

Novel peptide therapeutics to treat cystic fibrosis-related diabetes

Targeting inflammation to improve rescue of CFTR by modulator therapy

Therapeutic potential of CC-90009 for cystic fibrosis

Molecular Therapies for Cystic Fibrosis Lung Disease

Discovery of novel mechanisms that impact CFTR translation and contribute to cystic fibrosis pathogenesis

Clinical(29)

DartCF: The Dartmouth Cystic Fibrosis Research Center

A Phase 1b, Multi-center Study of IV Gallium Nitrate in Patients with Cystic Fibrosis who are colonized with Nontuberculosis Mycobacterium (The ABATE Study).

Evaluating Maternal and Neonatal Pharmacokinetics of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators - The ELECTRA Pregnancy Study

Impact of Pseudomonas aeruginosa cytochrome P450 enzymes and secondary metabolites on drug metabolism and disposition in the cystic fibrosis patient

Preparation for lung transplant discussions and decisions among people with cystic fibrosis

Understanding Oral Diseases in Cystic Fibrosis to Develop Tailored Preventive Dental Interventions

Targeting SGLTs for liver disease in a rabbit model of cystic fibrosis

Adenine Base Edited Correction of Cystic Fibrosis Airways

Tuning translation efficiency to overcome refractory defects in CFTR

Health Outcomes of Parents with Cystic Fibrosis (HOPe:CF)

Epi / Nat. History(8)

Regional monitoring of CF lung disease after changes in mechanical airway-clearance treatment

The Georgia Cystic Fibrosis Data Warehouse

A Dietary Intervention to Improve Glucose Tolerance in Adults with Cystic Fibrosis

Estrogen-mediated effects on neutrophil function and airway inflammatory response

The role of CFTR during macrophage-mediated killing of bacteria

Genetics, glycemic control and the microbiome in cystic fibrosis

Risk Factors For Worse Lung Function In Latinos With Cystic Fibrosis

Evolution of Pseudomonas aeruginosa in premise plumbing and impact on cystic fibrosis respiratory disease pathogenesis

Gene/Cell Therapy(23)

Cystic Fibrosis Gene Therapy with adeno-associated viral vectors

Development of a versatile paired prime editing toolkit for CFTR gene correction

Pharmacogenomic discovery of therapeutic targets for corrector-refractory cystic fibrosis

Editing basal cells for durable gene therapy of cystic fibrosis

Optimizing Surgical Transplant of CFTR Gene-Corrected Human Basal Stem Cells to the Upper Airway

Intein technology to deliver CFTR to CF airway using AAV

Combinatorial design of nonviral base editing systems for treating cystic fibrosis with nonsense mutations

Magnetic Microrobots Assist AAV4 for CFTR Gene Delivery Through Mucus Barrier

Leveraging CRISPR RNA-guided DNA Transposases for Gene Insertion at the CFTR Locus

Leveraging a 'sliding-window' Type I CRISPR base editing platform to correct CFTR null mutations

Biomarker / Dx(9)

Imaging and Molecular Phenotyping of Cystic Fibrosis Lung Disease

Modulation of Lung Disease by Genetic/Epigenetic Profiling

Antimicrobial peptides and antibiotic diffusion in sputum

SCH: Smart Breath- based Diagnosis of Pulmonary Exacerbations in Children with Cystic Fibrosis through Machine Learning: Towards Noninvasive Health Monitoring in Real-Time

Bacteriophage as a predictive biomarker in chronic Pseudomonas airway disease

Genetic Modifiers and Diagnostics for Bone Health in Cystic Fibrosis

Wearable Microfluidic Systems for Measuring Sweat Biomarkers in Cystic Fibrosis Patients During Exercise in Remote Settings

Quantitation and Spatial Registration of Airways Dysfunction with Dynamic 19F MRI in Cystic Fibrosis

Optimizing exercise for cystic fibrosis: Understanding immune modulation and identifying blood biomarkers

Other(8)

UAB CF Research and Translation Core Center

Delivering inhalable nanoparticles containing AI-optimized CFTR mRNA with a novel microfluidic device for treatment of CF

Inhibiting the cystic fibrosis transmembrane conductance regulator (CFTR) in the cervix as a novel approach to non-hormonal contraception

Dartmouth Cystic Fibrosis Training Program

Improving mutant KV11.1 trafficking to treat Long QT Syndrome

Rare mutations in Cystic Fibrosis: Overcoming barriers to personalized medicine

Arsenic related cystic fibrosis

Development and implementation of statistical machine learning methods to shorten rare disease odysseys