Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Digestive duplication cyst of the tongue is an extremely rare otorhinolaryngological malformation which occurs during early embryogenesis and is characterized by a single, and on occasion multiple, cystic lesion that is most frequently located in the anterior portion of the tongue, either deeply embedded within it or superficially on it. Depending mostly on size and location of the cyst, patients could be asymptomatic or could present a wide array of symptoms, such as varying degrees of respiratory and feeding difficulties, lingual swelling and protrusion, dysphagia, and more rarely, recurrent bleeding or brownish discharge from a lingual sinus.
Biomarker and diagnostic research for digestive duplication cyst of the tongue has been reported in the published literature.
No clinical trials have been registered for digestive duplication cyst of the tongue.
5 publications have been identified in PubMed for digestive duplication cyst of the tongue. Research spans Case Report / Case Series (60%), Diagnostic / Biomarker (20%), and Review / Meta-Analysis (20%).
Fleisher S (2026). [PMID: 41543476](https://pubmed.ncbi.nlm.nih.gov/41543476/). *The Journal of craniofacial surgery*. [Case Report / Case Series]
Vali S (2025). [PMID: 40959804](https://pubmed.ncbi.nlm.nih.gov/40959804/). *Journal of cytology*. [Diagnostic / Biomarker]
Maldonado A (2025). [PMID: 40350078](https://pubmed.ncbi.nlm.nih.gov/40350078/). *Journal of stomatology, oral and maxillofacial surgery*. [Case Report / Case Series]
Yin H (2025). [PMID: 39856729](https://pubmed.ncbi.nlm.nih.gov/39856729/). *World J Surg Oncol*. [Review / Meta-Analysis]
Pontes MTVM (2024). [PMID: 38439051](https://pubmed.ncbi.nlm.nih.gov/38439051/). *Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 8:13 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center