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A rare otorhinolaryngologic disease characterized by congenital, typically bilateral and paramedian, symmetric or asymmetric fistulae in the lower lip, which are lined by labial mucosa. The malformation is usually asymptomatic, although it may communicate with accessory salivary glands and then result in secretion of saliva from the opening. Infections may also occur.
No clinical trials have been registered for lower lip fistula.
3 publications have been identified in PubMed for lower lip fistula. Research spans Review / Meta-Analysis (33%), Case Report / Case Series (33%), and Clinical Trial Publication (33%).
Mani T (2026). [PMID: 42165654](https://pubmed.ncbi.nlm.nih.gov/42165654/). *Orthod Craniofac Res*. [Review / Meta-Analysis]
Lasky S (2025). [PMID: 39592184](https://pubmed.ncbi.nlm.nih.gov/39592184/). *Plast Reconstr Surg*. [Clinical Trial Publication]
Patel M (2024). [PMID: 38861357](https://pubmed.ncbi.nlm.nih.gov/38861357/). *J Craniofac Surg*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 7:14 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center