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Double-outlet left ventricle (DOLV) is an extremely rare congenital cardiac malformation in which both the aorta and the pulmonary artery arise, either exclusively or predominantly, from the morphologic left ventricle.
Biomarker and diagnostic research for double outlet left ventricle has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for double outlet left ventricle.
63 publications have been identified in PubMed for double outlet left ventricle. Research spans Case Report / Case Series (42%), Clinical Trial Publication (18%), and Epidemiology / Natural History (15%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 26 | 42% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 5:31 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Clinical study results
11 |
18% |
Disease patterns and progression | 9 | 15% |
Testing and diagnosis research | 7 | 11% |
Research summaries | 7 | 11% |
Laboratory research | 1 | 2% |
New treatment approaches | 1 | 2% |
Jesús RF (2026). [PMID: 42102628](https://pubmed.ncbi.nlm.nih.gov/42102628/). *J Electrocardiol*. [Epidemiology / Natural History]
Maya HA (2026). [PMID: 42092499](https://pubmed.ncbi.nlm.nih.gov/42092499/). *J Thorac Cardiovasc Surg*. [Clinical Trial Publication]
Griffith GJ (2026). [PMID: 41634884](https://pubmed.ncbi.nlm.nih.gov/41634884/). *Cardiol Young*. [Diagnostic / Biomarker]
Yamazaki Y (2026). [PMID: 41872899](https://pubmed.ncbi.nlm.nih.gov/41872899/). *Gen Thorac Cardiovasc Surg Cases*. [Case Report / Case Series]
Kowalczyk M (2026). [PMID: 42132139](https://pubmed.ncbi.nlm.nih.gov/42132139/). *Cardiol J*. [Case Report / Case Series]
Wakimoto M (2026). [PMID: 41930035](https://pubmed.ncbi.nlm.nih.gov/41930035/). *Cureus*. [Case Report / Case Series]
Alanís-Naranjo JM (2026). [PMID: 41563227](https://pubmed.ncbi.nlm.nih.gov/41563227/). *JACC Case Rep*. [Case Report / Case Series]
Chappell G (2026). [PMID: 40818789](https://pubmed.ncbi.nlm.nih.gov/40818789/). *J Thorac Cardiovasc Surg*. [Gene Therapy / Novel Therapeutics]
Kanji AM (2026). [PMID: 42027841](https://pubmed.ncbi.nlm.nih.gov/42027841/). *Radiol Case Rep*. [Case Report / Case Series]
Robinson J (2026). [PMID: 42079951](https://pubmed.ncbi.nlm.nih.gov/42079951/). *JTCVS Open*. [Epidemiology / Natural History]